Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 10/20 | 0.69 |
| ▸ | FLT1 | P17948 | 5/20 | 0.62 |
| ▸ | FLT4 | P35916 | 5/20 | 0.62 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993934 | 0.95 | KDR (0.70) | KDRFLT1FLT4CNR2HTR1A | |
| SCHEMBL7987725 | 0.92 | KDR (0.70) | KDRFLT1FLT4CNR2 | |
| SCHEMBL7554218 | 0.89 | KDR (0.71) | KDRFLT1FLT4CNR2HTR1A | |
| SCHEMBL7551199 | 0.88 | KDR (0.54) | KDRFLT1FLT4FLT3CNR2 | |
| SCHEMBL7547303 | 0.88 | KDR (0.53) | KDRFLT1FLT4CNR2HTR1A | |
| SCHEMBL7549676 | 0.86 | KDR (0.50) | KDRFLT1FLT4FLT3CNR2 | |
| SCHEMBL7554271 | 0.85 | KDR (0.49) | KDRFLT1FLT4FLT3CNR2 | |
| SCHEMBL7988115 | 0.85 | KDR (0.49) | KDRFLT1FLT4FLT3CNR2 | |
| SCHEMBL7550092 | 0.85 | KDR (0.49) | KDRFLT1FLT4FLT3CNR2 | |
| SCHEMBL7990971 | 0.83 | KDR (0.70) | KDRFLT1FLT4FLT3CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265403-B1 | TYROSINE INHIBITORS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |