SCHEMBL7990971 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	KDR	P35968	9/20	0.70

▸	FLT1	P17948	5/20	0.51

▸	FLT4	P35916	5/20	0.51

▸	CNR2	P34972	3/20	0.46

▸	FLT3	P36888	1/20	0.40

▸	HTR6	P50406	1/20	0.39

▸	CYP2A6	P11509	2/20	0.38

▸	PDGFRB	P09619	2/20	0.35

▸	PDGFRA	P16234	2/20	0.35

▸	HTR1D	P28221	1/20	0.35

▸	ALPL	P05186	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7549622	0.88	KDR (0.55)	KDRFLT1FLT4CNR2FLT3
SCHEMBL7986796	0.86	CNR2 (0.52)	KDRFLT1FLT4CNR2FLT3
SCHEMBL7554218	0.86	KDR (0.71)	KDRFLT1FLT4CNR2
SCHEMBL7555811	0.85	KDR (0.50)	KDRCNR2FLT3HTR6PDGFRB
SCHEMBL7993934	0.85	KDR (0.70)	KDRFLT1FLT4CNR2
SCHEMBL7994193	0.84	KDR (0.49)	KDRFLT1FLT4CNR2FLT3
SCHEMBL7990474	0.84	KDR (0.71)	KDRFLT1FLT4CNR2CYP2A6
SCHEMBL7990673	0.83	KDR (0.69)	KDRFLT1FLT4CNR2FLT3
SCHEMBL7553991	0.83	KDR (1.00)	KDRFLT1FLT4FLT3CYP2A6
SCHEMBL7987725	0.82	KDR (0.70)	KDRFLT1FLT4CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6265403-B1	TYROSINE INHIBITORS	MERCK & CO., INC.	2001-07-24	—	—	US	disclosed