Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | PDE9A | O76083 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GCGR | P47871 | 3/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1841756 | 0.82 | GPR84 (0.49) | GPR84TAAR1ROCK2ROCK1CYP3A4 | |
| SCHEMBL7992854 | 0.81 | GPR84 (0.41) | GPR84ROCK2ROCK1KMT2AGCGR | |
| SCHEMBL5382412 | 0.79 | CYP3A4 (0.41) | GPR84TAAR1ROCK2ROCK1CYP3A4 | |
| SCHEMBL7993027 | 0.77 | CA1 (0.40) | TAAR1ROCK2CYP3A4KMT2AGCGR | |
| SCHEMBL7978450 | 0.77 | GPR84 (0.44) | GPR84ROCK2GCGRMAPK14LMNA | |
| SCHEMBL7993029 | 0.76 | GPR84 (0.50) | GPR84KMT2AGSK3B | |
| SCHEMBL5390245 | 0.76 | PRKCA (0.43) | GPR84ROCK2KMT2AGSK3BHPGD | |
| SCHEMBL7978256 | 0.74 | HTR2A (0.43) | GPR84KMT2ALMNAHPGD | |
| SCHEMBL5375269 | 0.72 | CDC7 (0.43) | LMNAGSK3BHPGD | |
| SCHEMBL7992535 | 0.72 | PTGDR (0.50) | CYP3A4CYP2C9KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070727-A1 | 2-(ARYLALKYLAMINO)PYRIMIDONE DERIVATIVES AND 2-(HETEROARYLALKYLAMINO)PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | claimed |