Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.45 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 7/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990994 | 0.93 | HTR2A (0.52) | MTNR1AMTNR1BHTR2AMEN1KMT2A | |
| SCHEMBL7978256 | 0.86 | HTR2A (0.43) | MTNR1AMTNR1BHTR2AMEN1KMT2A | |
| SCHEMBL7993029 | 0.84 | GPR84 (0.50) | HTR2AMEN1KMT2AHTR6USP2 | |
| SCHEMBL7990813 | 0.81 | GPR84 (0.43) | MEN1KMT2AHTR6CDK2 | |
| SCHEMBL7996376 | 0.79 | POLB (0.53) | MTNR1AMTNR1BMEN1KMT2AMAPT | |
| SCHEMBL7996288 | 0.76 | MTNR1A (0.46) | PTGDRMTNR1AMTNR1BCYP3A4CYP2D6 | |
| SCHEMBL12845688 | 0.75 | MTNR1A (0.56) | PTGDRMTNR1AMTNR1BHTR2AIP6K1 | |
| SCHEMBL7990800 | 0.72 | GPR84 (0.49) | KMT2AMAPK1HPGDCYP3A4CYP2C9 | |
| SCHEMBL5390245 | 0.71 | PRKCA (0.43) | MEN1KMT2AMAPTHPGDCLK4 | |
| SCHEMBL8048232 | 0.70 | HTR2A (0.51) | PTGDRMTNR1AMTNR1BHTR2AIP6K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070727-A1 | 2-(ARYLALKYLAMINO)PYRIMIDONE DERIVATIVES AND 2-(HETEROARYLALKYLAMINO)PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | claimed |