Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 4/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993029 | 0.87 | GPR84 (0.50) | HTR2AGPR84HTR6HTR1AMEN1 | |
| SCHEMBL7992535 | 0.86 | PTGDR (0.50) | HTR2AHTR6MTNR1AMTNR1BMEN1 | |
| SCHEMBL7990813 | 0.81 | GPR84 (0.43) | GPR84HTR6HTR1AMEN1KMT2A | |
| SCHEMBL7990994 | 0.80 | HTR2A (0.52) | HTR2AHTR1AMPONOTUMMTNR1A | |
| SCHEMBL7978450 | 0.80 | GPR84 (0.44) | GPR84LMNA | |
| SCHEMBL7996376 | 0.76 | POLB (0.53) | MTNR1AMTNR1BMEN1KMT2ASLC6A4 | |
| SCHEMBL12845710 | 0.74 | HTR2A (0.52) | HTR2AGPR84HTR6HTR1ADRD2 | |
| SCHEMBL7990800 | 0.74 | GPR84 (0.49) | GPR84KMT2ALMNAHPGD | |
| SCHEMBL7993027 | 0.71 | CA1 (0.40) | MEN1KMT2A | |
| SCHEMBL5390245 | 0.70 | PRKCA (0.43) | GPR84MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070727-A1 | 2-(ARYLALKYLAMINO)PYRIMIDONE DERIVATIVES AND 2-(HETEROARYLALKYLAMINO)PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | claimed |