Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4385045 | 0.79 | L3MBTL1 (0.47) | L3MBTL1 | |
| SCHEMBL4378576 | 0.78 | PNMT (0.37) | PNMTFAAHCTSSCTSKMC4R | |
| SCHEMBL7974390 | 0.76 | TAAR1 (0.43) | IDO1 | |
| SCHEMBL4385050 | 0.76 | LMNA (0.48) | L3MBTL1 | |
| Oxalic Acid SCHEMBL7990786 | 0.73 | KDM4E (0.52) | FAAHL3MBTL1 | |
| SCHEMBL4386660 | 0.72 | PNMT (0.43) | PNMTMC4RIDO1TDO2 | |
| SCHEMBL2105356 | 0.72 | PNMT (0.43) | PNMTMC4RIDO1TDO2 | |
| SCHEMBL7971497 | 0.71 | MAPT (0.46) | — | |
| SCHEMBL4380977 | 0.71 | CTSC (0.43) | CTSLCTSBCTSSCTSKKCNH2 | |
| SCHEMBL223971 | 0.71 | TAAR1 (0.51) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |