Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403884 | 0.74 | KDM4E (0.43) | KDM4EGABRA5DGAT1L3MBTL1ALDH1A1 | |
| SCHEMBL2461154 | 0.74 | L3MBTL1 (0.56) | THRBKDM4EGABRA5L3MBTL1ALDH1A1 | |
| SCHEMBL1821132 | 0.73 | GBA1 (0.40) | THRBKDM4EGABRA5DGAT1L3MBTL1 | |
| SCHEMBL510047 | 0.73 | MAOB (0.49) | KDM4ECXCR2GABRA5CYP2C9CYP2C19 | |
| SCHEMBL12294290 | 0.72 | ATM (0.43) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL17006857 | 0.72 | ELOVL1 (0.57) | KDM4EL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL18402510 | 0.71 | KDM4E (0.38) | THRBKDM4EGABRA5DGAT1L3MBTL1 | |
| SCHEMBL19229877 | 0.71 | NUDT1 (0.43) | KDM4ECXCR1CXCR2GABRA5L3MBTL1 | |
| SCHEMBL21038121 | 0.71 | ELOVL1 (0.37) | KDM4ECXCR1CXCR2L3MBTL1ALDH1A1 | |
| SCHEMBL24907185 | 0.70 | ME2 (0.35) | KDM4EHDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180650-B1 | ANTIINFLAMMATORY AGENTS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTITUMOR AGENTS | MERCK FROSST CANADA & CO. (CA) | 2001-01-30 | — | — | US | disclosed |