Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 8/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989163 | 0.85 | PTPN11 (0.48) | PPARALMNAMAPK1L3MBTL1CA1 | |
| SCHEMBL7987979 | 0.84 | PPARA (0.46) | S1PR1PPARALMNAMAPK1L3MBTL1 | |
| SCHEMBL7991183 | 0.83 | KDM4E (0.49) | LMNAMAPK1L3MBTL1MAOAGAA | |
| SCHEMBL7994778 | 0.82 | SLC2A1 (0.41) | S1PR1PPARALMNAMAPK1L3MBTL1 | |
| SCHEMBL7987543 | 0.82 | ABCB1 (0.44) | S1PR1LMNAMAPK1S1PR3SMN1; SMN2 | |
| SCHEMBL7994780 | 0.81 | MAOB (0.53) | S1PR1L3MBTL1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL7988818 | 0.77 | MAOB (0.48) | MAPK1L3MBTL1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL7991609 | 0.75 | MAOB (0.49) | L3MBTL1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL7989235 | 0.72 | ACHE (0.48) | LMNAMAPK1L3MBTL1MAOAMAOB | |
| SCHEMBL9692772 | 0.70 | SLC2A1 (0.47) | S1PR1L3MBTL1S1PR3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055117-A1 | NOVEL ISOQUINOLINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2001-08-02 | — | — | WO | disclosed |