Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.55 |
| ▸ | DRD2 | P14416 | 8/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411187 | 0.77 | HTR2A (0.64) | HTR2ADRD2HTR1ADRD4 | |
| Hydrochloric Acid SCHEMBL11263432 | 0.77 | DRD2 (0.64) | HTR2ADRD2HTR1A | |
| Hydrochloric Acid SCHEMBL9411098 | 0.76 | HTR2A (0.63) | HTR2ADRD2DRD4 | |
| SCHEMBL10414446 | 0.76 | DRD2 (0.73) | HTR2ADRD2HTR1AHTR7DRD4 | |
| SCHEMBL7993630 | 0.75 | HTR1A (0.58) | HTR2ADRD2HTR1AHTR7 | |
| SCHEMBL9760169 | 0.75 | HTR2A (0.52) | HTR2ADRD2HTR1AHTR7DRD4 | |
| Hydrochloric Acid SCHEMBL7979099 | 0.74 | HTR1A (0.57) | HTR2ADRD2HTR1AHTR7 | |
| SCHEMBL11172181 | 0.74 | DRD2 (0.61) | HTR2ADRD2HTR1AHTR7DRD4 | |
| SCHEMBL11064274 | 0.74 | — | — | |
| SCHEMBL10414445 | 0.73 | DRD2 (0.73) | HTR2ADRD2HTR1AHTR7DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284775-B1 | PSYCHOLOGICAL DISORDERS | AVENTIS PHARMACEUTICALS INC. | 2001-09-04 | — | — | US | disclosed |
| US-5371087-A | Antipsychotic, analgesics, anticonvulsant and anxiolytic agent | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-12-06 | — | — | US | disclosed |
| US-5229388-A | 3-[4-(1-substituted-4-piperazinyl)butyl]-4-thiazolidinone and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-20 | — | — | US | disclosed |
| US-5037984-A | Anticonvulsants; anxiolytic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-08-06 | — | — | US | disclosed |
| US-4933453-A | ANTIPSYCHOTIC, ANALGESIC, ANTICONVULSANT, AND ANXIOLYTIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-06-12 | — | — | US | disclosed |