Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306648 | 0.88 | DRD4 (0.54) | HTR2ADRD4PARP1 | |
| SCHEMBL8307680 | 0.87 | HTR2A (0.65) | HTR2ADRD4DRD2HTR7HTR6 | |
| SCHEMBL7993630 | 0.84 | HTR1A (0.58) | HTR2ADRD2DRD3HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL7979099 | 0.83 | HTR1A (0.57) | HTR2ADRD2DRD3HTR1AHTR7 | |
| SCHEMBL8303726 | 0.80 | HTR2A (0.38) | HTR2ADRD4 | |
| SCHEMBL8302001 | 0.80 | PARP1 (0.48) | PARP1DRD2DRD3 | |
| SCHEMBL8446873 | 0.77 | DRD2 (0.45) | HTR2APARP1DRD2DRD3HTR1A | |
| SCHEMBL8302484 | 0.77 | PARP1 (0.47) | HTR2APARP1DRD2DRD3HTR1A | |
| SCHEMBL9759749 | 0.76 | PARP1 (0.46) | HTR2APARP1DRD2DRD3HTR1A | |
| SCHEMBL7979523 | 0.76 | HTR2A (0.56) | HTR2ADRD4DRD2HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041445-A | Antipsychotic agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-08-20 | — | — | US | claimed |