SCHEMBL526807

SCHEMBL526807

O=C1c2ccccc2C(=O)N1CCCO

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.68
ALDH1A1 P00352 3/20 0.63
MEN1 O00255 2/20 0.63
HTT P42858 2/20 0.63
KMT2A Q03164 2/20 0.63
RAB9A P51151 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
RGS12 O14924 1/20 0.63
NPC1 O15118 1/20 0.63
LMNA P02545 1/20 0.63
PABPC1 P11940 1/20 0.63
RECQL P46063 1/20 0.63
TSHR P16473 1/20 0.62
TDP1 Q9NUW8 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
MAPT P10636 1/20 0.58
GLS O94925 1/20 0.57
CYP1A2 P05177 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C19 P33261 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29459619 1.00 KDM4E (0.68) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL8632419 0.96 KDM4E (0.70) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL2554681 0.94 KDM4E (0.72) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL3468673 0.92 KDM4E (0.70) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL17275126 0.92 KDM4E (0.70) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL7296911 0.92 KDM4E (0.70) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL1448490 0.92 KDM4E (0.70) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL7352888 0.92 KDM4E (0.70) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL4179085 0.92 KDM4E (0.70) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL7544499 0.92 KDM4E (0.70) KDM4EALDH1A1MEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119390724-A Synthesis method of phosphorous acid diester compound 兰州大学 2025-02-07 CN claimed
CN-111116453-B Preparation method of N- (3-hydroxypropyl) phthalimide and catalyst used for method 万华化学集团股份有限公司 2024-08-20 CN claimed
US-20240209278-A1 AMINE-BOOSTED DETERGENT CHEVRON ORONITE COMPANY LLC 2024-06-27 US claimed
EP-4352188-A1 AMINE-BOOSTED DETERGENT Chevron Oronite Company LLC (US) 2024-04-17 EP claimed
CN-117597421-A Amine enhanced detergents 雪佛龙奥伦耐有限责任公司 2024-02-23 CN claimed
CN-114196023-B Surface modifier and application thereof in preparation of silicon-based composite functional coating material 中材高新江苏硅材料有限公司 2022-12-20 CN claimed
WO-2022259193-A1 AMINE-BOOSTED DETERGENT CHEVRON ORONITE COMPANY LLC (US) 2022-12-15 WO claimed
CN-114196023-A Surface modifier and application thereof in preparation of silicon-based composite functional coating material 中材高新江苏硅材料有限公司 2022-03-18 CN claimed
CN-111116453-A Preparation method of N- (3-hydroxypropyl) phthalimide and catalyst used in method 万华化学集团股份有限公司 2020-05-08 CN claimed
US-6187083-B1 INK COMPOSITION COMPRISING SELECTED INK VEHICLE, AMIDE VISCOSITY MODIFIER, CONDUCTIVE SULFONATE SALT ALL HAVING MELTING POINTS WITHIN SPECIFIED RANGE, COLORANT, OPTIONAL ANTIOXIDANT AND ULTRAVIOLET ABSORBER XEROX CORPORATION 2001-02-13 US claimed
EP-3886904-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-22 EP disclosed
US-12479858-B2 Macrocyclic compounds as sting agonists and methods and uses thereof LUPIN LIMITED (IN) 2025-11-25 US disclosed
CN-223096890-U Grinding device of N- (3-hydroxypropyl) phthalimide 大连金点生物科技有限公司 2025-07-15 CN disclosed
CN-223096890-U Grinding device of N- (3-hydroxypropyl) phthalimide 大连金点生物科技有限公司 2025-07-15 CN disclosed
US-12338210-B2 Degradable polymers and monomers therefor THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2025-06-24 US disclosed
WO-1986000902-A1 DERIVATIVES OF METHYLENE-BISPHOSPHONIC ACID, PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) 1986-02-13 WO disclosed
US-4395417-A Antihyperlipidemic compositions RESEARCH CORPORATION (US) 1983-07-26 US disclosed
US-4211703-A CHEMICAL INTERMEDIATES FOR CEPHALOSPORINS SMITHKLINE CORPORATION (US) 1980-07-08 US disclosed
US-4189573-A CHEMICAL INTERMEDIATES SMITHKLINE CORPORATION (US) 1980-02-19 US disclosed
US-4112086-A BACTERICIDE SMITHKLINE CORPORATION (US) 1978-09-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12479858-B2 Macrocyclic compounds as sting agonists and methods and uses thereof STING1, CGAS, MAVS KDM4E 4476/4885ALDH1A1 4861/4885MEN1 1550/4885
US-12338210-B2 Degradable polymers and monomers therefor HDHD5, LTA4H, KYNU KDM4E 487/4885ALDH1A1 168/4885MEN1 179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.