Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912078 | 0.92 | CA1 (0.44) | RAB9ASMN1; SMN2CA1CA2CA9 | |
| SCHEMBL10909622 | 0.86 | CA1 (0.55) | SMN1; SMN2CA1CA2CA9CA4 | |
| SCHEMBL10913065 | 0.84 | MAPT (0.59) | RAB9ASMN1; SMN2MAPTHDAC7ALDH1A1 | |
| SCHEMBL10909799 | 0.81 | POLB (0.46) | SMN1; SMN2MAPTPOLBALDH1A1MEN1 | |
| SCHEMBL10913832 | 0.80 | KMT2A (0.41) | RAB9ASMN1; SMN2MAPTPOLBHDAC7 | |
| Dimethylamine SCHEMBL10909871 | 0.79 | PDE10A (0.41) | RAB9ASMN1; SMN2MAPTPOLBPDE10A | |
| SCHEMBL7991341 | 0.79 | ALDH1A1 (0.51) | RAB9ASMN1; SMN2MAPTPOLBANPEP | |
| SCHEMBL10912179 | 0.78 | KMT2A (0.45) | RAB9ASMN1; SMN2MAPTPOLBALDH1A1 | |
| SCHEMBL10909868 | 0.78 | ALDH1A1 (0.46) | RAB9ASMN1; SMN2MAPTPOLBALDH1A1 | |
| Dimethylamine SCHEMBL10913743 | 0.78 | RAB9A (0.41) | RAB9ASMN1; SMN2MAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |