Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MRE11 | P49959 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993372 | 0.87 | MMP3 (0.38) | MRE11MMP3KMT2AALDH1A1KDM4E | |
| SCHEMBL7594254 | 0.86 | CYP3A4 (0.34) | MMP3ALDH1A1TSHRCYP3A4KDM4E | |
| SCHEMBL7394692 | 0.77 | TDP1 (0.44) | L3MBTL1NPC1ATMEGLN1TDP1 | |
| SCHEMBL7395958 | 0.76 | TSHR (0.34) | L3MBTL1NPC1KMT2AALDH1A1TSHR | |
| SCHEMBL7979052 | 0.71 | TP53 (0.39) | L3MBTL1NPC1MMP3TDP1KMT2A | |
| SCHEMBL7991480 | 0.69 | MMP3 (0.50) | L3MBTL1NPC1ATMMMP3KMT2A | |
| SCHEMBL20522561 | 0.69 | MAOB (0.44) | L3MBTL1NPC1TDP1SLC6A2SLC6A3 | |
| SCHEMBL28396741 | 0.67 | ALDH1A1 (0.55) | L3MBTL1NPC1ATMEGLN1TDP1 | |
| SCHEMBL7392898 | 0.67 | TDP1 (0.54) | L3MBTL1NPC1ATMEGLN1TDP1 | |
| SCHEMBL7631721 | 0.66 | ALDH1A1 (0.58) | L3MBTL1NPC1ATMEGLN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |