Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979052 | 0.85 | TP53 (0.39) | MMP3L3MBTL1NPC1ALDH1A1LMNA | |
| SCHEMBL7994042 | 0.84 | L3MBTL1 (0.50) | MMP3L3MBTL1NPC1ATMDHODH | |
| SCHEMBL7394692 | 0.76 | TDP1 (0.44) | L3MBTL1NPC1ATMALDH1A1LMNA | |
| SCHEMBL7993470 | 0.72 | MMP3 (0.47) | MMP3L3MBTL1NPC1DHODHALDH1A1 | |
| SCHEMBL7997188 | 0.72 | MMP3 (0.40) | MMP3L3MBTL1NPC1ATMMEN1 | |
| SCHEMBL7993209 | 0.71 | MMP3 (0.79) | MMP3NPC1MTNR1AMEN1KMT2A | |
| Acetic Acid Methyl Ester SCHEMBL10581477 | 0.69 | ALDH1A1 (0.57) | NPC1ALDH1A1LMNAMTNR1AMEN1 | |
| SCHEMBL7991389 | 0.69 | L3MBTL1 (0.35) | MMP3L3MBTL1NPC1ATMALDH1A1 | |
| SCHEMBL7990513 | 0.69 | MMP3 (0.67) | MMP3L3MBTL1NPC1ALDH1A1MTNR1A | |
| SCHEMBL7997116 | 0.68 | MMP3 (0.69) | MMP3L3MBTL1NPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |