Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HPD | P32754 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988818 | 0.91 | MAOB (0.48) | MAOBMRGPRX4SRD5A2VNN1MAOA | |
| SCHEMBL7994780 | 0.90 | MAOB (0.53) | MAOBMRGPRX4SRD5A2NR4A2SMPD1 | |
| SCHEMBL7989235 | 0.87 | ACHE (0.48) | MAOBSMPD1MAOARAB9ATP53 | |
| SCHEMBL7991437 | 0.87 | KDM4E (0.48) | MAOBMRGPRX4SRD5A2VNN1 | |
| SCHEMBL7991147 | 0.83 | MAOB (0.47) | MAOBMAOARAB9ATP53SMN1; SMN2 | |
| SCHEMBL7994703 | 0.80 | KDM4E (0.45) | MAOBMRGPRX4SRD5A2NR4A2RAB9A | |
| SCHEMBL7977331 | 0.78 | KDM4E (0.49) | SMPD1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7991229 | 0.78 | KDM4E (0.49) | RAB9ANPC1 | |
| SCHEMBL7992415 | 0.78 | KDM4E (0.51) | MRGPRX4SMPD1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7988142 | 0.78 | KDM4E (0.53) | MRGPRX4SMPD1RAB9APKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055117-A1 | NOVEL ISOQUINOLINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2001-08-02 | — | — | WO | disclosed |