Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.53 |
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988818 | 0.92 | MAOB (0.48) | MAOBMAOASRD5A2NPC1RAB9A | |
| SCHEMBL7991609 | 0.90 | MAOB (0.49) | MAOBMAOASRD5A2NPC1RAB9A | |
| SCHEMBL7989235 | 0.87 | ACHE (0.48) | MAOBMAOANPC1RAB9AL3MBTL1 | |
| SCHEMBL7987543 | 0.84 | ABCB1 (0.44) | POLBSMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7991147 | 0.84 | MAOB (0.47) | MAOBMAOANPC1RAB9AL3MBTL1 | |
| SCHEMBL7989163 | 0.83 | PTPN11 (0.48) | L3MBTL1SMPD1 | |
| SCHEMBL7994778 | 0.82 | SLC2A1 (0.41) | MAOBMAOANPC1RAB9AL3MBTL1 | |
| SCHEMBL7988142 | 0.80 | KDM4E (0.53) | NPC1RAB9AMRGPRX4SMN1; SMN2KDM4E | |
| SCHEMBL7987979 | 0.80 | PPARA (0.46) | MAOBMAOANPC1RAB9AL3MBTL1 | |
| SCHEMBL7991229 | 0.79 | KDM4E (0.49) | NPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055117-A1 | NOVEL ISOQUINOLINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2001-08-02 | — | — | WO | disclosed |