Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 4/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | FRK | P42685 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.40 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991678 | 0.93 | HTT (0.40) | CNOT7GSK3BPRKD3MAP4K4FRK | |
| SCHEMBL7984242 | 0.93 | CNOT7 (0.45) | CNOT7TSHRKDM4EMAPK1LMNA | |
| SCHEMBL7974043 | 0.88 | GBA1 (0.43) | CNOT7TSHRKDM4EMAPK1LMNA | |
| SCHEMBL7985603 | 0.88 | CNOT7 (0.41) | CNOT7TSHRKDM4EMAPK1LMNA | |
| SCHEMBL7984490 | 0.88 | CNOT7 (0.41) | CNOT7TSHRKDM4EMAPK1LMNA | |
| SCHEMBL7974441 | 0.86 | GRK2 (0.43) | CNOT7TSHRADORA3ADORA2A | |
| SCHEMBL7974615 | 0.86 | ADORA2A (0.44) | CNOT7ADORA3ADORA2AADORA1 | |
| SCHEMBL7992303 | 0.84 | CNOT7 (0.40) | CNOT7TSHRCSNK1DKDM4EMAPK1 | |
| SCHEMBL7988802 | 0.84 | NPC1 (0.44) | CNOT7TSHRKDM4EMAPK1LMNA | |
| SCHEMBL7974291 | 0.83 | CNOT7 (0.39) | CNOT7TSHRKDM4EMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |