Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984406 | 0.93 | CASR (0.43) | CNOT7CASRPIK3CAMTORPIK3CG | |
| SCHEMBL7984242 | 0.91 | CNOT7 (0.45) | CNOT7TSHRKDM4ELMNAPOLB | |
| SCHEMBL7986355 | 0.89 | SIGMAR1 (0.42) | CNOT7TSHROPRM1KDM4ELMNA | |
| SCHEMBL7974291 | 0.89 | CNOT7 (0.39) | CNOT7TSHRKDM4ELMNAPOLB | |
| SCHEMBL7987628 | 0.89 | PDE4B (0.40) | CNOT7TSHRKDM4ELMNAPOLB | |
| SCHEMBL7984897 | 0.87 | GAA (0.46) | TSHROPRM1LMNAMAPK1FAAH | |
| SCHEMBL7985336 | 0.86 | PIK3CA (0.42) | MAPK1PIK3CAMTORPIK3CGADORA3 | |
| SCHEMBL7991652 | 0.84 | CNOT7 (0.42) | CNOT7TSHRKDM4ELMNAPOLB | |
| SCHEMBL7974043 | 0.84 | GBA1 (0.43) | CNOT7TSHRKDM4ELMNAPOLB | |
| SCHEMBL7974615 | 0.84 | ADORA2A (0.44) | CNOT7ADORA3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |