Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984683 | 0.94 | CNOT7 (0.37) | CNOT7FAAHADORA2AADORA1DPP4 | |
| SCHEMBL7992303 | 0.89 | CNOT7 (0.40) | CNOT7FAAHTSHRKDM4ELMNA | |
| SCHEMBL7984242 | 0.89 | CNOT7 (0.45) | CNOT7TSHRKDM4ELMNAPOLB | |
| SCHEMBL7985603 | 0.88 | CNOT7 (0.41) | CNOT7FAAHTSHRKDM4ELMNA | |
| SCHEMBL7986355 | 0.88 | SIGMAR1 (0.42) | CNOT7FAAHTSHRKDM4ELMNA | |
| SCHEMBL7987628 | 0.88 | PDE4B (0.40) | CNOT7TSHRKDM4ELMNAPOLB | |
| SCHEMBL7987253 | 0.87 | HPGDS (0.40) | MAPK1ADORA2AADORA1 | |
| SCHEMBL7984897 | 0.85 | GAA (0.46) | FAAHTSHRLMNAMAPK1ADORA2A | |
| SCHEMBL7991669 | 0.84 | HDAC1 (0.38) | DRD2 | |
| SCHEMBL7985791 | 0.83 | CYP11B1 (0.40) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |