Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 2/20 | 0.40 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.40 |
| ▸ | DHPS | P49366 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986327 | 0.94 | NPC1 (0.43) | GBA1NPC1RAB9APDE5ACNOT7 | |
| SCHEMBL7984242 | 0.90 | CNOT7 (0.45) | CNOT7TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL7991652 | 0.88 | CNOT7 (0.42) | CNOT7TSHRKDM4ELMNAPOLB | |
| SCHEMBL7974286 | 0.87 | DHPS (0.49) | GBA1NPC1RAB9APDE5ACNOT7 | |
| SCHEMBL7992303 | 0.84 | CNOT7 (0.40) | CNOT7TSHRKDM4ELMNAPOLB | |
| SCHEMBL7974615 | 0.83 | ADORA2A (0.44) | CNOT7ALDH1A1HTT | |
| SCHEMBL7985603 | 0.83 | CNOT7 (0.41) | CNOT7TSHRKDM4ELMNAPOLB | |
| SCHEMBL7984490 | 0.83 | CNOT7 (0.41) | CNOT7TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL7986355 | 0.82 | SIGMAR1 (0.42) | CNOT7TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL7974291 | 0.82 | CNOT7 (0.39) | CNOT7TSHRKDM4ELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |