Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992024 | 0.92 | AR (0.58) | ARGAARAB9AMAPTNPBWR1 | |
| SCHEMBL7988441 | 0.89 | AR (0.55) | ARGAARAB9AMAPTNPBWR1 | |
| SCHEMBL28914603 | 0.88 | AR (0.54) | ARGAARAB9AMAPTNPBWR1 | |
| SCHEMBL7989862 | 0.88 | AR (0.54) | ARGAARAB9AMAPTNPBWR1 | |
| SCHEMBL7992254 | 0.87 | MAPT (0.54) | ARGAARAB9AMAPTNPBWR1 | |
| SCHEMBL7995187 | 0.87 | AR (0.53) | SIRT2SIRT1ARGAARAB9A | |
| SCHEMBL7988102 | 0.86 | MAPT (0.54) | ARGAARAB9AMAPTNPBWR1 | |
| SCHEMBL7977720 | 0.86 | AR (0.52) | ARGAARAB9AMAPTNPBWR1 | |
| SCHEMBL7977722 | 0.85 | NPBWR1 (0.53) | ARGAARAB9AMAPTNPBWR1 | |
| SCHEMBL7991922 | 0.84 | AR (0.50) | ARGAARAB9AMAPTNPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |