Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24424563 | 0.81 | SCN5A (0.35) | POLBPIK3R1PIK3CASCN5AHDAC4 | |
| SCHEMBL1892615 | 0.81 | USP7 (0.38) | LMNAPIK3R1PIK3CASCN5AHDAC4 | |
| SCHEMBL2171161 | 0.79 | DHFR (0.44) | JAK2POLBPIK3R1PIK3CASCN5A | |
| SCHEMBL20713184 | 0.79 | NPC1 (0.53) | LMNAPOLBKDM4EALDH1A1GAA | |
| SCHEMBL2317617 | 0.79 | ALDH1A3 (0.33) | PIK3R1PIK3CASCN5AHDAC4KDM4E | |
| SCHEMBL24857504 | 0.79 | PIK3R1 (0.36) | PIK3R1PIK3CASCN5AHDAC4KDM4E | |
| SCHEMBL3265976 | 0.78 | DHODH (0.57) | LMNAPOLBHDAC4KDM4EHSD17B10 | |
| SCHEMBL24857447 | 0.77 | CA2 (0.34) | PIK3R1PIK3CASCN5AHDAC4KDM4E | |
| SCHEMBL2173235 | 0.77 | MAT2A (0.38) | POLBPIK3R1PIK3CASCN5AHDAC4 | |
| SCHEMBL4970466 | 0.76 | SCN5A (0.32) | PIK3R1PIK3CASCN5AHDAC4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001096335-A1 | IMIDAZO[1,2-A]PYRIDINE ETHER COMPOUNDS AS ION CHANNEL MODULATORS | CARDIOME PHARMA CORP. (CA) | 2001-12-20 | — | — | WO | disclosed |