Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7992078

CCOC(=O)Cc1cc2c(s1)CCN(C(=O)[C@H](Cc1ccc([N+](=O)[O-])cc1)NC(=O)C=CC1CCNCC1)C2.O=C(O)C(F)(F)F

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 4/20 0.35
ITGA2B P08514 4/20 0.35
ADORA1 P30542 1/20 0.35
P2RX7 Q99572 1/20 0.32
HCRTR2 O43614 3/20 0.32
SLC5A1 P13866 1/20 0.32
SLC5A2 P31639 1/20 0.32
BACE1 P56817 1/20 0.31
MAPT P10636 1/20 0.31
KCNJ1 P48048 1/20 0.30
WDR5 P61964 1/20 0.30
KMT2A Q03164 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
HCRTR1 O43613 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7985585 0.87 ADORA1 (0.38) ITGB3ITGA2BADORA1P2RX7MAPT
Hydrochloric Acid SCHEMBL7986192 0.83 ITGB3 (0.39) ITGB3ITGA2BADORA1P2RX7HCRTR2
Trifluoroacetic Acid SCHEMBL8133864 0.81 ITGB3 (0.55) ITGB3ITGA2BADORA1P2RX7HCRTR2
SCHEMBL7985559 0.81 ADORA1 (0.50) ITGB3ITGA2BADORA1P2RX7HCRTR2
Trifluoroacetic Acid SCHEMBL7989225 0.81 ITGB3 (0.48) ITGB3ITGA2BADORA1P2RX7HCRTR2
SCHEMBL7992026 0.81 ITGB3 (0.35) ITGB3ITGA2BADORA1P2RX7KMT2A
Trifluoroacetic Acid SCHEMBL7975353 0.79 ITGB3 (0.44) ITGB3ITGA2BADORA1P2RX7HCRTR2
SCHEMBL7988424 0.77 ITGB3 (0.57) ITGB3ITGA2BADORA1P2RX7HCRTR2
SCHEMBL7974860 0.77 YAP1 (0.40) ITGB3ITGA2BADORA1P2RX7MAPT
Hydrochloric Acid SCHEMBL7986317 0.77 ITGB3 (0.56) ITGB3ITGA2BADORA1P2RX7HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265418-B1 ANTICOAGULANTS UBE INDUSTRIES, LTD. (JP) 2001-07-24 US disclosed
EP-1020467-A1 N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF UBE INDUSTRIES LIMITED (JP) 2000-07-19 EP disclosed