SCHEMBL7992391

SCHEMBL7992391

[CH2]OC1CCN(COC(C)=O)CC1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 1/20 0.37
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
BCHE P06276 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7992499 0.81 ENO1 (0.34)
SCHEMBL7986102 0.79 SLC18A3 (0.37) SLC18A3ALDH1A1LMNAHSD17B10BCHE
SCHEMBL7989717 0.77 SLC18A3 (0.36) SLC18A3ALDH1A1LMNAHSD17B10BCHE
SCHEMBL7975128 0.77 SLC18A3 (0.36) SLC18A3ALDH1A1LMNAHSD17B10SMN1; SMN2
SCHEMBL5036796 0.74 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10SMN1; SMN2
SCHEMBL7975125 0.74 SLC18A3 (0.36) SLC18A3ALDH1A1LMNAHSD17B10BCHE
SCHEMBL6695501 0.72 ALDH1A1 (0.41) ALDH1A1LMNAHSD17B10SMN1; SMN2
SCHEMBL16285109 0.71 TEAD3 (0.40) ALDH1A1LMNAHSD17B10
SCHEMBL7989633 0.71 EPHX2 (0.44) ALDH1A1SMN1; SMN2
SCHEMBL8986692 0.69 TSHR (0.46) ALDH1A1LMNAHSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265418-B1 ANTICOAGULANTS UBE INDUSTRIES, LTD. (JP) 2001-07-24 US disclosed
EP-1020467-A1 N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF UBE INDUSTRIES LIMITED (JP) 2000-07-19 EP disclosed