Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
| ▸ | NPC1 | O15118 | 7/20 | 0.74 |
| ▸ | RAB9A | P51151 | 7/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4076346 | 0.85 | NPC1 (1.00) | LMNATP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17342638 | 0.81 | KMT2A (0.66) | LMNATP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7980666 | 0.81 | RAB9A (0.74) | LMNATP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7980860 | 0.80 | NPC1 (0.62) | LMNATP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3758954 | 0.79 | MTNR1A (0.60) | LMNATSHRNPSR1MEN1KMT2A | |
| SCHEMBL7980669 | 0.79 | NPC1 (0.80) | LMNATP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7994882 | 0.79 | NPC1 (0.80) | LMNATP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17148053 | 0.79 | NPC1 (0.84) | LMNATP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24970053 | 0.78 | MTNR1A (0.63) | LMNATSHRNPSR1KMT2AMTNR1B | |
| SCHEMBL5623097 | 0.78 | NPC1 (0.68) | LMNATP53NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294502-B1 | Thermally-responsive record material | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-25 | — | — | US | claimed |
| WO-1999061251-A1 | THERMALLY-RESPONSIVE RECORD MATERIAL CONTAINING A CARBAMATE COMPONENT | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-02 | — | — | WO | claimed |
| US-6294502-B1 | Thermally-responsive record material | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-25 | — | — | US | disclosed |
| WO-1999061251-A1 | THERMALLY-RESPONSIVE RECORD MATERIAL CONTAINING A CARBAMATE COMPONENT | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-02 | — | — | WO | disclosed |