SCHEMBL4076346

SCHEMBL4076346

O=C(Nc1ccccc1)OCCOc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 1.00
RAB9A P51151 5/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
TSHR P16473 1/20 1.00
MEN1 O00255 4/20 0.80
KMT2A Q03164 4/20 0.80
LMNA P02545 1/20 0.80
TP53 P04637 1/20 0.80
NPSR1 Q6W5P4 2/20 0.66
RECQL P46063 1/20 0.64
CYP1A2 P05177 1/20 0.63
CYP3A4 P08684 1/20 0.63
CYP2C9 P11712 1/20 0.63
CYP2C19 P33261 1/20 0.63
THRB P10828 1/20 0.54
HPGD P15428 1/20 0.54
CRHBP P24387 1/20 0.54
CRHR2 Q13324 1/20 0.54
FAAH O00519 2/20 0.54
KCNA5 P22460 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10597414 0.90 NPC1 (0.82) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL7980669 0.89 NPC1 (0.80) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL17342583 0.89 NPC1 (0.80) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL7994779 0.89 NPC1 (0.80) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL7980732 0.89 NPC1 (0.80) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL7994882 0.89 NPC1 (0.80) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL7995040 0.87 RAB9A (0.76) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL7980666 0.85 RAB9A (0.74) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL7992902 0.85 LMNA (0.78) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL17346621 0.84 NPC1 (0.72) NPC1RAB9ASMN1; SMN2TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6294502-B1 Thermally-responsive record material BAYER AKTIENGESELLSCHAFT (DE) 2001-09-25 US claimed
US-6015771-A ENHANCED IMAGE INTENSITY OR IMPROVED THERMAL RESPONSE, CARBAMATE BAYER AKTIENGESELLSCHAFT (DE) 2000-01-18 US claimed
WO-1999061251-A1 THERMALLY-RESPONSIVE RECORD MATERIAL CONTAINING A CARBAMATE COMPONENT BAYER AKTIENGESELLSCHAFT (DE) 1999-12-02 WO claimed
EP-3758947-B1 HEAT SENSITIVE RECORDING MATERIAL AND COLOR DEVELOPER SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2025-05-14 EP disclosed
US-11512048-B2 Heat sensitive recording material, and color developer SOLENIS TECHNOLOGIES, L.P. (US) 2022-11-29 US disclosed
CN-112601668-B Thermosensitive recording material and color-developing agent 索理思科技开曼公司 2022-07-29 CN disclosed
CN-112601668-A Thermosensitive recording material and color-developing agent 索理思科技开曼公司 2021-04-02 CN disclosed
US-20210002215-A1 HEAT SENSITIVE RECORDING MATERIAL AND COLOR DEVELOPER SOLENIS TECHNOLOGIES CAYMAN, L.P. (KY) 2021-01-07 US disclosed
EP-3758947-A1 HEAT SENSITIVE RECORDING MATERIAL AND COLOR DEVELOPER Solenis Technologies Cayman, L.P. (KY) 2021-01-06 EP disclosed
EP-3533619-A1 HEAT SENSITIVE RECORDING MATERIAL AND COLOR DEVELOPER BASF SE (DE) 2019-09-04 EP disclosed
EP-2794558-B1 HEAT SENSITIVE COATING COMPOSITION BASF SE (DE) 2017-04-26 EP disclosed
EP-2121853-A1 HEAT-SENSITIVE COATING COMPOSITIONS BASED ON RESORCINYL TRIAZINE DERIVATIVES BASF SE (DE) 2009-11-25 EP disclosed
US-7517397-B2 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. (US) 2009-04-14 US disclosed
WO-2008110487-A1 HEAT-SENSITIVE COATING COMPOSITIONS BASED ON RESORCINYL TRIAZINE DERIVATIVES BASF SE (CH) 2008-09-18 WO disclosed
US-20060240981-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2006-10-26 US disclosed
EP-1622858-A2 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2006-02-08 EP disclosed
WO-2004099116-A2 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-11-18 WO disclosed
US-6294502-B1 Thermally-responsive record material BAYER AKTIENGESELLSCHAFT (DE) 2001-09-25 US disclosed
US-6015771-A ENHANCED IMAGE INTENSITY OR IMPROVED THERMAL RESPONSE, CARBAMATE BAYER AKTIENGESELLSCHAFT (DE) 2000-01-18 US disclosed
WO-1999061251-A1 THERMALLY-RESPONSIVE RECORD MATERIAL CONTAINING A CARBAMATE COMPONENT BAYER AKTIENGESELLSCHAFT (DE) 1999-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210002215-A1 HEAT SENSITIVE RECORDING MATERIAL AND COLOR DEVELOPER SCN1A, NCS1, SCN4A NPC1 4413/4885RAB9A 2012/4885SMN1; SMN2 565/4885
US-11512048-B2 Heat sensitive recording material, and color developer SCN1A, NCS1, SCN5A NPC1 4325/4885RAB9A 2153/4885SMN1; SMN2 574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.