Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 13/20 | 0.57 |
| ▸ | CDK2 | P24941 | 13/20 | 0.57 |
| ▸ | CCNE2 | O96020 | 11/20 | 0.57 |
| ▸ | CDK4 | P11802 | 7/20 | 0.57 |
| ▸ | CDK1 | P06493 | 6/20 | 0.57 |
| ▸ | CCND1 | P24385 | 6/20 | 0.57 |
| ▸ | CCNB2 | O95067 | 5/20 | 0.57 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.57 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.57 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | CCND2 | P30279 | 1/20 | 0.39 |
| ▸ | CCND3 | P30281 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216993 | 0.72 | CCNE1 (1.00) | CCNE1CDK2CCNE2CDK4CDK1 | |
| SCHEMBL1260011 | 0.67 | MAPK1 (0.42) | CCNE1CDK2CCNE2CDK4CDK1 | |
| SCHEMBL22684986 | 0.66 | CSNK2A2 (0.47) | CCNE1CDK2CCNE2CDK4CDK1 | |
| SCHEMBL5840422 | 0.65 | KDR (0.72) | CCNE1CDK2CCNE2LIMK1CDK5 | |
| SCHEMBL27035775 | 0.65 | PDK4 (0.47) | CCNE1CDK2CCNE2CDK4CDK1 | |
| SCHEMBL9285608 | 0.64 | ALDH1A1 (0.51) | CCNE1CDK2CCNE2CDK4CDK1 | |
| SCHEMBL28014843 | 0.64 | KDR (0.62) | CCNE1CDK2CDK5 | |
| SCHEMBL1716179 | 0.64 | LIMK1 (0.41) | CCNE1CDK2LIMK1CDK5 | |
| SCHEMBL16513227 | 0.64 | LIMK1 (0.46) | CCNE1CDK2CCNE2CDK4CDK1 | |
| SCHEMBL28247393 | 0.64 | LIMK1 (0.49) | CCNE1CDK2LIMK1CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262096-B1 | IN COMBINATION WITH A MODULATOR OF P53 TRANSACTIVATION FORMULATED AS A FIXED DOSE. | BRISTOL-MYERS SQUIBB COMPANY | 2001-07-17 | — | — | US | disclosed |