Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1303791 | 0.78 | MAOA (0.50) | MAOAMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL1303082 | 0.68 | FAAH (0.54) | FAAH | |
| SCHEMBL1302719 | 0.61 | FAAH (0.50) | MAOAMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL8006548 | 0.61 | MAOA (0.46) | MAOAMAOBALDH1A1FAAHNPSR1 | |
| SCHEMBL1302990 | 0.61 | MAOA (0.46) | MAOAMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL7994247 | 0.60 | FAAH (0.40) | MAOAMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL12106886 | 0.59 | FAAH (0.48) | MAOAMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL1304208 | 0.58 | FAAH (0.55) | MAOAMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL8006299 | 0.56 | PTGS2 (0.42) | FAAHLMNA | |
| SCHEMBL5981491 | 0.56 | ALDH1A1 (0.40) | MAOAMAOBALDH1A1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009152025-A1 | IMIDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH | MERCK & CO., INC. (US) | 2009-12-17 | — | — | WO | disclosed |