Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.45 |
| ▸ | MMP13 | P45452 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995243 | 0.90 | MMP1 (0.46) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7993340 | 0.87 | MMP1 (0.56) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6995857 | 0.81 | MMP1 (0.46) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6995225 | 0.79 | MMP1 (0.42) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6995230 | 0.79 | MMP1 (0.42) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7001941 | 0.78 | MMP1 (0.56) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6998853 | 0.78 | MMP1 (0.56) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7993343 | 0.72 | ALDH1A1 (0.33) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7303606 | 0.71 | MMP1 (0.43) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7002033 | 0.70 | MMP1 (0.55) | MMP1MMP13MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288246-B1 | REACTION OF HYDROXYLAMINE WITH ALKYLSILYL HALIDE, HYDROLYSIS WITH ACID | PFIZER INC | 2001-09-11 | — | — | US | disclosed |
| EP-0949244-A2 | Process for preparing hydroxamic acids | Pfizer Products Inc. (US) | 1999-10-13 | — | — | EP | disclosed |