SCHEMBL7993792

SCHEMBL7993792

C=Cc1ccccc1C(CC)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.45
LMNA P02545 3/20 0.37
HSD17B10 Q99714 1/20 0.37
TSHR P16473 2/20 0.36
CYP1A2 P05177 1/20 0.36
AKR1C3 P42330 4/20 0.35
AKR1C2 P52895 4/20 0.35
AKR1C1 Q04828 1/20 0.35
PTGS1 P23219 1/20 0.35
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
HTR1A P08908 1/20 0.35
ADRA1A P35348 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
CRHBP P24387 2/20 0.34
CRHR2 Q13324 2/20 0.34
KCNQ2 O43526 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27629109 0.85 CYP1A2 (0.37) CYP2C19LMNAHSD17B10TSHRCYP1A2
SCHEMBL7262264 0.85 LMNA (0.40) CYP2C19LMNAHSD17B10TSHRCYP1A2
SCHEMBL10483555 0.84 GBA1 (0.42) CYP2C19HSD17B10ALDH1A1POLBMEN1
SCHEMBL28024342 0.82 CSNK1E (0.43) CYP2C19ALDH1A1
SCHEMBL10870208 0.82 CSNK1E (0.43) CYP2C19ALDH1A1
SCHEMBL28634960 0.81 ALDH1A1 (0.36) LMNATSHRALDH1A1MEN1KMT2A
SCHEMBL27537238 0.78 SLC1A2 (0.37) CYP2C19LMNACYP1A2PTGS1MEN1
SCHEMBL177911 0.78 ALDH1A1 (0.40) LMNATSHRALDH1A1POLBMEN1
SCHEMBL9748533 0.78 CYP2C19 (0.46) CYP2C19LMNAHSD17B10CYP1A2AKR1C3
SCHEMBL27420968 0.78 GABBR2 (0.40) LMNATSHRCYP1A2POLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6013411-A PHOTOSENSITIVE COMPOSITION WITH HOMO OR COPOLYCARBONS, HALOGENIUM COMPOUNDS AND SULFONIUM COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 2000-01-11 US disclosed