Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4062734 | 0.83 | LMNA (0.41) | CYP2C19GABRA1GABRB2ALDH1A1HSD17B10 | |
| SCHEMBL6406721 | 0.83 | CYSLTR2 (0.45) | CYP2C19ALDH1A1 | |
| SCHEMBL7167286 | 0.81 | PTGS2 (0.46) | CYP2C19ADRA2AADRA2BADRA2CGABRA1 | |
| SCHEMBL21409442 | 0.80 | KMT2A (0.40) | KDM4EALDH1A1GAAHSD17B10CYP1A2 | |
| SCHEMBL10952808 | 0.79 | CYP2C19 (0.60) | CYP2C19GABRA1GABRB2ALDH1A1CYP1A2 | |
| SCHEMBL7691515 | 0.79 | LMNA (0.42) | CYP2C19ADRA2AADRA2BADRA2CGABRA1 | |
| SCHEMBL4941343 | 0.79 | TSHR (0.39) | ALDH1A1HSD17B10CYP1A2AKR1C3AKR1C2 | |
| SCHEMBL11736053 | 0.78 | GABRA1 (0.43) | GABRA1GABRB2HSD17B10AKR1C3AKR1C2 | |
| SCHEMBL6395365 | 0.78 | L3MBTL1 (0.44) | ALDH1A1HSD17B10CYP1A2AKR1C3AKR1C2 | |
| SCHEMBL7993792 | 0.78 | CYP2C19 (0.45) | CYP2C19ALDH1A1HSD17B10CYP1A2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192492-B1 | PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-01-02 | — | — | EP | claimed |
| EP-0192492-B1 | PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-01-02 | — | — | EP | disclosed |
| US-4677193-A | GONADOTROPIN-RELEASING FACTOR ANALOGS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1987-06-30 | — | — | US | disclosed |
| EP-0192492-A2 | Peptides containing an aliphatic-aromatic ketone side chain | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1986-08-27 | — | — | EP | disclosed |