Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7991351 | 0.99 | LMNA (0.41) | LMNAGAAHTTCHEK1ABCB1 | |
| SCHEMBL7990254 | 0.93 | KDM4E (0.41) | LMNAGAACHEK1CYP11B2POLB | |
| SCHEMBL7997014 | 0.90 | HTR7 (0.44) | CHEK1ABCB1ABCG2HTR7DRD2 | |
| SCHEMBL7979506 | 0.89 | ABCB1 (0.52) | LMNAGAACHEK1ABCB1ABCG2 | |
| Bromide SCHEMBL8218997 | 0.89 | HTR7 (0.43) | CHEK1ABCB1ABCG2HTR7DRD2 | |
| SCHEMBL7996949 | 0.88 | PTK2 (0.47) | LMNAGAAHTTDRD2DRD4 | |
| Bromide SCHEMBL7993380 | 0.88 | ABCB1 (0.51) | LMNAGAACHEK1ABCB1ABCG2 | |
| SCHEMBL7979110 | 0.87 | DRD4 (0.46) | HTTDRD2DRD4POLBDRD3 | |
| SCHEMBL7991687 | 0.87 | DRD2 (0.43) | GAAHTR7DRD2DRD4CYP11B2 | |
| Hydrochloric Acid SCHEMBL7991375 | 0.86 | DRD4 (0.45) | HTTHTR7DRD2DRD4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288230-B1 | COMPOUNDS FOR TREATMENT OF PSYCHOLOGICAL DISORDERS | NEUROGEN CORPORATION | 2001-09-11 | — | — | US | claimed |