Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4653784 | 0.84 | HTR1A (0.54) | MTNR1AMTNR1BSRD5A2LMNAMEN1 | |
| SCHEMBL25267 | 0.78 | MTNR1A (0.62) | MTNR1AMTNR1BMEN1KMT2ANPC1 | |
| SCHEMBL10377782 | 0.75 | MTNR1A (0.42) | MTNR1AMTNR1BSRD5A2ITKLMNA | |
| SCHEMBL16686988 | 0.75 | MTNR1A (0.49) | MTNR1AMTNR1BKDM4E | |
| SCHEMBL1137563 | 0.75 | HTR1B (0.53) | LMNAMEN1KMT2AKDM4EMAPT | |
| SCHEMBL5768529 | 0.74 | SRD5A2 (0.61) | MTNR1AMTNR1BSRD5A2RHEBMAPT | |
| SCHEMBL14154752 | 0.73 | MTNR1A (0.48) | MTNR1AMTNR1BLMNAMEN1KMT2A | |
| SCHEMBL12435547 | 0.73 | MTNR1A (0.48) | MTNR1AMTNR1BLMNAMEN1KMT2A | |
| Acetic Acid SCHEMBL11383873 | 0.73 | MTNR1A (0.45) | MTNR1AMTNR1BSRD5A2MEN1KMT2A | |
| SCHEMBL24451623 | 0.72 | MTNR1A (0.45) | MTNR1AMTNR1BMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001044185-A1 | CARBON MONOXIDE-BASED SYNTHESIS OF SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-06-21 | — | — | WO | disclosed |