SCHEMBL25267

SCHEMBL25267

CCc1cc2c(OC)cccc2[nH]1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 5/20 0.62
MTNR1B P49286 5/20 0.62
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
ATM Q13315 2/20 0.50
FLT3 P36888 2/20 0.48
RHEB Q15382 1/20 0.44
POLB P06746 1/20 0.44
IDO1 P14902 1/20 0.44
ABCG2 Q9UNQ0 1/20 0.44
NR3C1 P04150 1/20 0.44
PGR P06401 1/20 0.44
NR3C2 P08235 1/20 0.44
HRH4 Q9H3N8 1/20 0.44
RCE1 Q9Y256 1/20 0.42
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2156821 0.87 MTNR1A (0.64) MTNR1AMTNR1BMEN1KMT2ANPC1
SCHEMBL10934841 0.85 MTNR1A (0.59) MTNR1AMTNR1BMEN1KMT2ANPC1
SCHEMBL24583898 0.85 MTNR1A (0.63) MTNR1AMTNR1BMEN1KMT2ANPC1
SCHEMBL24451623 0.82 MTNR1A (0.45) MTNR1AMTNR1BMEN1KMT2ANPC1
SCHEMBL13632220 0.82 MTNR1A (0.57) MTNR1AMTNR1BMEN1KMT2ANPC1
SCHEMBL27980445 0.81 MTNR1A (0.56) MTNR1AMTNR1BMEN1KMT2ANPC1
SCHEMBL24459343 0.81 MTNR1A (0.45) MTNR1AMTNR1BMEN1KMT2ANPC1
SCHEMBL19447299 0.81 MTNR1A (0.44) MTNR1AMTNR1BMEN1KMT2ANPC1
SCHEMBL24104984 0.80 MTNR1A (0.61) MTNR1AMTNR1BMEN1KMT2ANPC1
SCHEMBL28586501 0.80 MTNR1A (0.65) MTNR1AMTNR1BMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220400673-A1 METHODS FOR WEED GROWTH CONTROL Mustgrow Biologics Corp. (CA) 2022-12-22 US disclosed
US-11358953-B2 Functionalized peptides as antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2022-06-14 US disclosed
WO-2022109755-A1 METHODS FOR CONTROLLING FUSARIUM WILT OF BANANA PLANTS Mustgrow Biologics Corp. (CA) 2022-06-02 WO disclosed
US-20220162217-A1 NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2022-05-26 US disclosed
US-11319325-B1 Macrocyclic spiropyrrolidine derived antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2022-05-03 US disclosed
WO-2022082311-A1 METHODS AND COMPOSITIONS COMPRISING HERBICIDALLY ACTIVE COMPOUNDS AND THIOCYANATE COMPOUNDS FOR CONTROLLING WEED GROWTH Mustgrow Biologics Corp. (CA) 2022-04-28 WO disclosed
US-20220073499-A1 FUNCTIONALIZED PEPTIDES AS ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2022-03-10 US disclosed
WO-2021077214-A1 METHODS FOR WEED GROWTH CONTROL Mustgrow Biologics Corp. (CA) 2021-04-29 WO disclosed
CN-110770211-A α unsaturated amide compound 协和麒麟株式会社 2020-02-07 CN disclosed
EP-1950200-B1 [[3-(2-amino-1,2-dioxoethyl)-2-ethyl-1-(phenylmethyl)-11H-indol-4-yl]oxy]acetic acid methyl ester as sPLA2 inhibitor LILLY CO ELI (US) 2012-01-11 EP disclosed
WO-1999016453-A1 METHOD FOR THE TREATMENT OF CYSTIC FIBROSIS ELI LILLY AND COMPANY (US) 1999-04-08 WO disclosed
WO-1999009978-A1 METHOD FOR TREATMENT OF NON-RHEUMATOID ATHRITIS ELI LILLY AND COMPANY (US) 1999-03-04 WO disclosed
WO-1998047508-A1 METHOD FOR THE TREATMENT OF STROKE USING N-HETEROCYCLIC GLYOXYLAMIDE COMPOUNDS SHIONOGI & CO., LTD. (JP) 1998-10-29 WO disclosed
WO-1998047507-A1 METHOD FOR THE TREATMENT OF STROKE USING N-HETEROCYCLIC GLYOXYLAMIDE COMPOUNDS SHIONOGI & CO., LTD. (JP) 1998-10-29 WO disclosed
WO-1998042343-A1 METHOD FOR TREATMENT OF CHRONIC BRONCHITIS ELI LILLY AND COMPANY (US) 1998-10-01 WO disclosed
US-5733923-A SECRETORY PANCREATIC PHOSPHOLIPASE A2 ELI LILLY AND COMPANY (US) 1998-03-31 US disclosed
US-5684034-A INHIBITORS OF HUMAN NON-PANCREATIC SECRETORY PHOSPHOLIPASE A2, TREATMENT OF SEPTIC SHOCK, TRAUMA, RESPIRATORY DISORDERS, RHEUMATIC ARTHRITIS, INHIBITORS OF ARACHIDONIC ACID RELEASE ELI LILLY AND COMPANY (US) 1997-11-04 US disclosed
US-5654326-A SEPTIC SHOCK; HUMAN NONPANCREATIC SECRETORY PHOSPHOLIPASE ELI LILLY AND COMPANY (US) 1997-08-05 US disclosed
EP-0675110-A1 1H-Indole-3-glyoxylamide sPLA2 inhibitors ELI LILLY AND COMPANY (US) 1995-10-04 EP disclosed
EP-0620215-A1 1H-indole-3-acetamide derivatives as sPLA2 inhibitors ELI LILLY AND COMPANY (US) 1994-10-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220073499-A1 FUNCTIONALIZED PEPTIDES AS ANTIVIRAL AGENTS SARS1, VIP, ACE MTNR1A 3517/4885MTNR1B 3396/4885MEN1 3626/4885
US-11319325-B1 Macrocyclic spiropyrrolidine derived antiviral agents ACE, ACE2, PKD1 MTNR1A 4181/4885MTNR1B 3950/4885MEN1 2278/4885
US-20220400673-A1 METHODS FOR WEED GROWTH CONTROL TST, NOTUM, GLO1 MTNR1A 3012/4885MTNR1B 2447/4885MEN1 4209/4885
US-11358953-B2 Functionalized peptides as antiviral agents SARS1, VIP, ACE MTNR1A 3517/4885MTNR1B 3396/4885MEN1 3626/4885
US-20220162217-A1 NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS ACE, ACE2, REN MTNR1A 3984/4885MTNR1B 3919/4885MEN1 4560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.