SCHEMBL7993986

SCHEMBL7993986

CN(C)C(=S)N(C)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.59
PHGDH O43175 1/20 0.59
MGLL Q99685 1/20 0.59
CA12 O43570 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
CA9 Q16790 1/20 0.59
LMNA P02545 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
ALDH1A1 P00352 4/20 0.48
MAPT P10636 2/20 0.48
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
HSP90AA1 P07900 1/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41
POLB P06746 1/20 0.41
KDM4E B2RXH2 1/20 0.41
TAS2R38 P59533 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25137386 0.90 FAAH (0.64) FAAHPHGDHMGLLCA12CA1
SCHEMBL8661742 0.82 FAAH (0.55) FAAHPHGDHMGLLCA12CA1
SCHEMBL14273121 0.81 FAAH (0.48) FAAHPHGDHMGLLCA12CA1
SCHEMBL9665382 0.81 ALDH1A1 (0.54) FAAHPHGDHMGLLCA12CA1
SCHEMBL8848450 0.80 FAAH (0.64) FAAHPHGDHMGLLCA12CA1
SCHEMBL15775368 0.79 FAAH (0.52) FAAHPHGDHMGLLCA12CA1
SCHEMBL5961342 0.78 FAAH (0.61) FAAHPHGDHMGLLCA12CA1
SCHEMBL7814241 0.77 ALDH1A1 (0.50) FAAHPHGDHMGLLCA12CA1
SCHEMBL1224111 0.76 FAAH (0.59) FAAHPHGDHMGLLCA12CA1
SCHEMBL2232383 0.76 ALDH1A1 (0.60) FAAHPHGDHMGLLCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20230120996-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-20 US disclosed
US-6287230-B1 Power transmission belt and elastomer composition BANDO CHEMICAL INDUSTRIES LTD. (JP) 2001-09-11 US disclosed
EP-1008625-A1 Power transmission belt and elastomer composition Bando Chemical Industries Ltd. (JP) 2000-06-14 EP disclosed
EP-0750010-B1 Power transmission belt BANDO CHEMICAL IND (JP) 1999-11-10 EP disclosed
EP-0750010-A1 Power transmission belt Bando Chemical Industries, Ltd. (JP) 1996-12-27 EP disclosed
US-5153331-A Reacting 6-epoxyethyl-3-oxatricyclo 3.2.1.0(2,4)!octane with a thiocyanate salt and/or a thiourea NIPPON OIL COMPANY, LTD. (JP) 1992-10-06 US disclosed
EP-0452092-A2 6-Epithioethyl-3-oxatricyclo (3.2.1.02.4) octane and process for preparation thereof NIPPON OIL CO. LTD. (JP) 1991-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP FAAH 2818/4885PHGDH 1455/4885MGLL 62/4885
US-20230120996-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP FAAH 2818/4885PHGDH 1455/4885MGLL 62/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.