Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994113 | 1.00 | NFE2L2 (0.42) | NFE2L2MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8346366 | 0.86 | MAPT (0.48) | NFE2L2MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8346367 | 0.86 | MAPT (0.48) | NFE2L2MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8346999 | 0.85 | TUBB4A (0.45) | NFE2L2MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7993260 | 0.85 | MAPT (0.44) | MAPTALDH1A1HPGDSMN1; SMN2PTGS1 | |
| SCHEMBL8343855 | 0.85 | CYP19A1 (0.52) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7993262 | 0.85 | MAPT (0.44) | MAPTALDH1A1HPGDSMN1; SMN2PTGS1 | |
| SCHEMBL8346996 | 0.85 | TUBB4A (0.45) | NFE2L2MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8343851 | 0.85 | CYP19A1 (0.52) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL8348299 | 0.83 | NQO2 (0.54) | MAPTALDH1A1HPGDSMN1; SMN2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000020005-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING AN OPIATE ANALGESIC AND A SYNERGIZING SUBSTANCE | EGIS Gyógyszergyár Rt. (HU) | 2000-04-13 | — | — | WO | claimed |
| WO-2000020005-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING AN OPIATE ANALGESIC AND A SYNERGIZING SUBSTANCE | EGIS Gyógyszergyár Rt. (HU) | 2000-04-13 | — | — | WO | disclosed |