Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348300 | 1.00 | NQO2 (0.54) | NQO2ABCB1MAOAMAOBTUBB4A | |
| SCHEMBL8346366 | 0.87 | MAPT (0.48) | NQO2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8346367 | 0.87 | MAPT (0.48) | NQO2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8346999 | 0.86 | TUBB4A (0.45) | NQO2ABCB1MAOAMAOBTUBB4A | |
| SCHEMBL8343851 | 0.86 | CYP19A1 (0.52) | NQO2ABCB1MAPTKDM4EMEN1 | |
| SCHEMBL8343855 | 0.86 | CYP19A1 (0.52) | NQO2ABCB1MAPTKDM4EMEN1 | |
| SCHEMBL7993262 | 0.86 | MAPT (0.44) | NQO2ABCB1TUBB4ATUBBTUBA3C | |
| SCHEMBL8346996 | 0.86 | TUBB4A (0.45) | NQO2ABCB1MAOAMAOBTUBB4A | |
| SCHEMBL7993260 | 0.86 | MAPT (0.44) | NQO2ABCB1TUBB4ATUBBTUBA3C | |
| SCHEMBL7994111 | 0.83 | NFE2L2 (0.42) | ABCB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942506-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, ANXIETY | GIS GYOGYSZERGYAR RT. (HU) | 1999-08-24 | — | — | US | claimed |
| US-5942506-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, ANXIETY | GIS GYOGYSZERGYAR RT. (HU) | 1999-08-24 | — | — | US | disclosed |