SCHEMBL7994145

SCHEMBL7994145

Cc1ccc(C(=O)C(=CC#N)c2ccc(C)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.54
CES1 P23141 3/20 0.54
ALDH1A1 P00352 8/20 0.44
LMNA P02545 4/20 0.44
HTT P42858 3/20 0.44
NPSR1 Q6W5P4 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
PKM P14618 2/20 0.44
ATM Q13315 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HPGD P15428 2/20 0.44
NLRP1 Q9C000 1/20 0.44
NTSR1 P30989 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
EGFR P00533 1/20 0.43
ERBB2 P04626 1/20 0.43
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20959565 0.81 CES2 (0.50) CES2CES1ALDH1A1LMNANPSR1
SCHEMBL11881089 0.76 CES2 (0.62) CES2CES1ALDH1A1LMNAHTT
SCHEMBL2349040 0.76 CES2 (0.44) CES2CES1ALDH1A1LMNANPSR1
SCHEMBL7896358 0.76 RAB9A (0.63) ALDH1A1LMNANPSR1SMN1; SMN2PKM
SCHEMBL14189755 0.74 PDE4A (0.55) ALDH1A1LMNAHTTNPSR1SMN1; SMN2
SCHEMBL13930325 0.74 GABRA1 (0.34) CES2CES1ALDH1A1LMNAHTT
SCHEMBL625933 0.72 GABRA1 (0.53) CES2CES1ALDH1A1LMNAHTT
SCHEMBL625934 0.72 GABRA1 (0.53) CES2CES1ALDH1A1LMNAHTT
SCHEMBL625935 0.72 GABRA1 (0.53) CES2CES1ALDH1A1LMNAHTT
SCHEMBL167254 0.72 CES2 (1.00) CES2CES1ALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975224-A1 PROCESS AND COMPOSITIONS FOR ENHANCING RELIABILITY OF EXOGENOUS CHEMICAL SUBSTANCES APPLIED TO PLANTS MONSANTO COMPANY (US) 2000-02-02 EP disclosed
US-6020287-A USING MIXTURE OF HERBICIDE AND PHENYL-SUBSTITUTED OLEFIN COMPOUND MONSANTO COMPANY (US) 2000-02-01 US disclosed
WO-1998033385-A1 PROCESS AND COMPOSITIONS FOR ENHANCING RELIABILITY OF EXOGENOUS CHEMICAL SUBSTANCES APPLIED TO PLANTS MONSANTO COMPANY (US) 1998-08-06 WO disclosed