Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.52 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | S100B | P04271 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591875 | 0.98 | HTR6 (0.50) | HTR6TERTCYP2A6LPAR5HTR1A | |
| SCHEMBL7594713 | 0.86 | HTR3A (0.57) | HTR6CYP2A6HTR1ADRD2ALDH1A1 | |
| SCHEMBL30584886 | 0.86 | HTR6 (0.52) | HTR6TERTCYP2A6ALDH1A1MEN1 | |
| SCHEMBL12004436 | 0.83 | HTR3E (0.54) | HTR6CYP2A6HTR1ADRD2HTT | |
| SCHEMBL7527390 | 0.83 | MAPT (0.48) | HTR6CYP2A6HTR1ADRD2ALDH1A1 | |
| SCHEMBL19212285 | 0.83 | HTR6 (0.54) | HTR6CYP2A6HTR1ADRD2MAPT | |
| SCHEMBL13871957 | 0.81 | HTR6 (0.39) | HTR6TERTCYP2A6LPAR5HTR1A | |
| SCHEMBL13113731 | 0.81 | MEN1 (0.45) | HTR6TERTCYP2A6LPAR5HTR1A | |
| SCHEMBL13113108 | 0.79 | MEN1 (0.46) | HTR6CYP2A6LPAR5HTR1ADRD2 | |
| SCHEMBL13871946 | 0.79 | IDO1 (0.38) | HTR6TERTCYP2A6LPAR5HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281356-B1 | ANTICANRCER AGENTS | HOFFMANN-LA ROCHE INC. | 2001-08-28 | — | — | US | disclosed |