Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | KHK | P50053 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594713 | 0.87 | HTR3A (0.57) | HTR6DRD2HTR1AHTR3AMAPT | |
| SCHEMBL7591875 | 0.85 | HTR6 (0.50) | HTR6DRD2HTR1AHTR3AFAAH | |
| SCHEMBL7527390 | 0.84 | MAPT (0.48) | HTR6DRD2HTR1AFAAHMAPT | |
| SCHEMBL7994183 | 0.83 | HTR6 (0.52) | HTR6DRD2HTR1AHTR3AFAAH | |
| SCHEMBL12004436 | 0.81 | HTR3E (0.54) | HTR6DRD2HTR1AHTR3AKHK | |
| SCHEMBL12806786 | 0.73 | HTR3A (0.72) | HTR1AHTR3AMAPTKDM4ERXFP1 | |
| SCHEMBL20242900 | 0.73 | HTR6 (0.56) | HTR6DRD2HTR1AHTR3AMAPT | |
| SCHEMBL7258870 | 0.72 | LMNA (0.64) | DRD2HTR1AHTR3AMAPTSIGMAR1 | |
| SCHEMBL13113721 | 0.71 | HTR6 (0.46) | HTR6DRD2HTR1AHTR3AMAPT | |
| SCHEMBL5750019 | 0.71 | KDM4E (0.56) | HTR6DRD2HTR1AFAAHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414216-B1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2020-10-21 | — | — | EP | disclosed |
| EP-3414216-B1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2020-10-21 | — | — | EP | disclosed |
| US-20190040028-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2019-02-07 | — | — | US | disclosed |
| US-20190040028-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2019-02-07 | — | — | US | disclosed |
| EP-3414216-A1 | ARYLATION OF ALIPHATIC AMINES | AAA Chemistry ApS (DK) | 2018-12-19 | — | — | EP | disclosed |
| WO-2017137047-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2017-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040028-A1 | ARYLATION OF ALIPHATIC AMINES | NAT1, AHR, ABL1 | HTR6 315/4885DRD2 226/4885HTR1A 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.