Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.60 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.56 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL58080 | 0.95 | TDP1 (0.58) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL29403879 | 0.95 | TDP1 (0.58) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL45486 | 0.92 | TDP1 (0.60) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| Benzene SCHEMBL28328708 | 0.90 | TDP1 (0.54) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL3756498 | 0.88 | TDP1 (0.56) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL30257990 | 0.88 | TDP1 (0.56) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL187542 | 0.86 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL8698196 | 0.86 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL9921900 | 0.86 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL2413345 | 0.86 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9522870-B2 | 2,5-disubstituted-1,4-diaminobenzenes | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2016-12-20 | — | — | US | claimed |
| US-20130237725-A1 | 2,5-DISUBSTITUTED-1,4-DIAMINOBENZENES | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2013-09-12 | — | — | US | claimed |
| US-11174258-B2 | Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes | IDEMITSU KOSAN CO., LTD. (JP) | 2021-11-16 | — | — | US | disclosed |
| US-20190002469-A1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO., LTD. (JP) | 2019-01-03 | — | — | US | disclosed |
| US-20180037590-A1 | SUBSTITUTED QUINOLINES AS PDE-10 INHIBITORS | SUNOVION PHARMACEUTICALS INC. | 2018-02-08 | — | — | US | disclosed |
| US-9834564-B2 | Substituted quinolines as PDE-10 inhibitors | SUNOVION PHARMACEUTICALS INC. (US) | 2017-12-05 | — | — | US | disclosed |
| US-9834564-B2 | Substituted quinolines as PDE-10 inhibitors | SUNOVION PHARMACEUTICALS INC. (US) | 2017-12-05 | — | — | US | disclosed |
| WO-2017093958-A1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO., LTD. (JP) | 2017-06-08 | — | — | WO | disclosed |
| US-9653745-B2 | Block copolymer, manufacturing method therefor, and polymer electrolyte material, molded polymer electrolyte, and solid-polymer fuel cell using said block copolymer | TORAY INDUSTRIES, INC. (JP) | 2017-05-16 | — | — | US | disclosed |
| US-9653745-B2 | Block copolymer, manufacturing method therefor, and polymer electrolyte material, molded polymer electrolyte, and solid-polymer fuel cell using said block copolymer | TORAY INDUSTRIES, INC. (JP) | 2017-05-16 | — | — | US | disclosed |
| EP-2749585-B1 | BLOCK COPOLYMER, MANUFACTURING METHOD THEREFOR, AND POLYMER ELECTROLYTE MATERIAL, MOLDED POLYMER ELECTROLYTE, AND SOLID-POLYMER FUEL CELL USING SAID BLOCK COPOLYMER | TORAY INDUSTRIES (JP) | 2017-03-22 | — | — | EP | disclosed |
| US-20140193742-A1 | BLOCK COPOLYMER, MANUFACTURING METHOD THEREFOR, AND POLYMER ELECTROLYTE MATERIAL, MOLDED POLYMER ELECTROLYTE, AND SOLID-POLYMER FUEL CELL USING SAID BLOCK COPOLYMER | TORAY INDUSTRIES, INC. (JP) | 2014-07-10 | — | — | US | disclosed |
| US-20140193742-A1 | BLOCK COPOLYMER, MANUFACTURING METHOD THEREFOR, AND POLYMER ELECTROLYTE MATERIAL, MOLDED POLYMER ELECTROLYTE, AND SOLID-POLYMER FUEL CELL USING SAID BLOCK COPOLYMER | TORAY INDUSTRIES, INC. (JP) | 2014-07-10 | — | — | US | disclosed |
| US-20130237725-A1 | 2,5-DISUBSTITUTED-1,4-DIAMINOBENZENES | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2013-09-12 | — | — | US | disclosed |
| US-20130237725-A1 | 2,5-DISUBSTITUTED-1,4-DIAMINOBENZENES | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2013-09-12 | — | — | US | disclosed |
| US-20130237725-A1 | 2,5-DISUBSTITUTED-1,4-DIAMINOBENZENES | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2013-09-12 | — | — | US | disclosed |
| US-20130158003-A1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2013-06-20 | — | — | US | disclosed |
| US-20130158003-A1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2013-06-20 | — | — | US | disclosed |
| WO-2011150156-A2 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2011-12-01 | — | — | WO | disclosed |
| EP-2003452-A1 | Method for diagnosing an allergy | Universität für Bodenkultur Wien (AT) | 2008-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037590-A1 | SUBSTITUTED QUINOLINES AS PDE-10 INHIBITORS | PDE10A, PDE2A, PDE3A | TDP1 189/4885ATM 1951/4885ALDH1A1 559/4885 |
| US-20130237725-A1 | 2,5-DISUBSTITUTED-1,4-DIAMINOBENZENES | DDT, PARP2, DDX42 | TDP1 777/4885ATM 1159/4885ALDH1A1 143/4885 |
| US-11174258-B2 | Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes | KCNH2, KCNH3, KCNJ2 | TDP1 3736/4885ATM 3865/4885ALDH1A1 397/4885 |
| US-20190002469-A1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES | KCNH2, KCNH3, KCNJ2 | TDP1 3736/4885ATM 3865/4885ALDH1A1 397/4885 |
| US-20130158003-A1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | COMT, GPR119, NLN | TDP1 2326/4885ATM 3942/4885ALDH1A1 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.