Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994551 | 0.87 | HDAC1 (0.39) | HDAC1HDAC6LTA4HADAMTS5HTT | |
| SCHEMBL7994486 | 0.81 | HDAC6 (0.41) | HDAC1HDAC6LTA4HMEN1ALDH1A1 | |
| SCHEMBL7997738 | 0.79 | LMNA (0.41) | HDAC1HDAC6LTA4HHTTMEN1 | |
| SCHEMBL7984361 | 0.76 | SMN1; SMN2 (0.36) | HTTALDH1A1 | |
| SCHEMBL7998619 | 0.76 | TP53 (0.35) | ALDH1A1 | |
| SCHEMBL7994388 | 0.75 | SMN1; SMN2 (0.40) | HTTMEN1ALDH1A1KMT2A | |
| SCHEMBL7984069 | 0.74 | SMN1; SMN2 (0.39) | HTTMEN1ALDH1A1KMT2A | |
| SCHEMBL7994556 | 0.68 | HDAC1 (0.41) | HDAC1HDAC6LTA4HMEN1ALDH1A1 | |
| SCHEMBL7997378 | 0.66 | LMNA (0.41) | HDAC1HDAC6LTA4HHTTMEN1 | |
| SCHEMBL7996157 | 0.65 | CYP11B1 (0.52) | HTTMEN1ALDH1A1KMT2ACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |