Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | TTR | P02766 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | APEX1 | P27695 | 2/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2403631 | 0.88 | GLO1 (0.67) | KDM4EMAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL79945 | 0.83 | GLO1 (0.71) | KDM4EMAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL2910901 | 0.77 | SNCA (0.73) | KDM4EMAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL7585198 | 0.76 | HSD17B10 (0.62) | KDM4EMAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL2221673 | 0.74 | KDM4E (0.74) | KDM4EMAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL5598948 | 0.74 | KDM4E (0.74) | KDM4EMAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL6535158 | 0.72 | TTR (0.66) | KDM4EMAPTHSD17B10KMT2AMEN1 | |
| Caffeic Acid SCHEMBL7064846 | 0.72 | KDM4E (1.00) | KDM4EMAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL2042662 | 0.72 | KDM4E (0.71) | KDM4EMAPTHSD17B10KMT2AMEN1 | |
| Caffeic Acid SCHEMBL1262229 | 0.72 | KDM4E (1.00) | KDM4EMAPTHSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002026697-A2 | AROMATIC DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | PHARMACOR, INC. (CA) | 2002-04-04 | — | — | WO | disclosed |