Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PER2 | O15055 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.36 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14402681 | 0.95 | PER2 (0.40) | MAPTHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15178138 | 0.88 | CYP2D6 (0.40) | MAPTHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15178118 | 0.88 | CYP2D6 (0.40) | MAPTHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9670060 | 0.84 | HTR1A (0.44) | CSNK1EMAPTHPGDALDH1A1THRA | |
| SCHEMBL11078194 | 0.83 | ALDH1A1 (0.38) | MAPTHPGDCYP2D6ALDH1A1USP2 | |
| SCHEMBL4828322 | 0.81 | MAPT (0.39) | CSNK1EMAPTHPGDCYP1A2CYP2C9 | |
| SCHEMBL28510962 | 0.80 | MAOB (0.43) | MAPTCYP2D6PER2ALDH1A1HTT | |
| SCHEMBL23870570 | 0.80 | MAPT (0.39) | CSNK1EMAPTHPGDCYP1A2CYP2C9 | |
| SCHEMBL28265187 | 0.80 | MAPT (0.39) | CSNK1EMAPTHPGDCYP1A2CYP2C9 | |
| SCHEMBL23870572 | 0.80 | LMNA (0.50) | CSNK1EMAPTHPGDCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001051481-A1 | METHOD FOR THE SYNTHESIS OF 6N-PENTYL-2H-PYRAN-2-ONE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2001-07-19 | — | — | WO | disclosed |