Known targets — ChEMBL curated mechanism
S1PR1S1PR2S1PR3S1PR4S1PR5rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.78 |
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | GLA | P06280 | 1/20 | 0.78 |
| ▸ | HPGD | P15428 | 1/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.78 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.78 |
| ▸ | BLM | P54132 | 1/20 | 0.78 |
| ▸ | CA1 | P00915 | 11/20 | 0.52 |
| ▸ | CA2 | P00918 | 11/20 | 0.52 |
| ▸ | CA9 | Q16790 | 9/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | CA3 | P07451 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL15283 | 0.96 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL831819 | 0.96 | RECQL (0.78) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL7537883 | 0.96 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL7537830 | 0.96 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Octadecyl Sulfate SCHEMBL9771950 | 0.96 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL23674209 | 0.96 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL11022896 | 0.96 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL18315185 | 0.96 | RECQL (0.78) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL21641350 | 0.96 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL355997 | 0.96 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114287075-A | Conductive composition for secondary battery | 广东省皓智科技有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-114287075-A | Conductive composition for secondary battery | 广东省皓智科技有限公司 | 2022-04-05 | — | — | CN | disclosed |
| US-6284435-B1 | FOR SOLID STATE ELECTRICAL DEVICES SUCH AS LIGHT-EMITTING DIODES | UNIAX CORPORATION | 2001-09-04 | — | — | US | disclosed |
| US-5965281-A | THE ADDITION OF A HIGHLY POLARIZABLE ADDITIVE, AN ORGANIC ANIONIC SURFACTANT, TO AN ELECTROLUMINESCENT CONJUGATED ORGANIC POLYMER TO IMPROVE THE EXTERNAL EFFICIENCY AND BRIGHTNESS VERSUS VOLTAGE RATIO AND ELECTRON INJECTION | UNIAX CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0440362-B1 | 2,2-Dimethyl-1-nitrilo or 2,2-dimethyl-1-hydroxylamino-3-(alkyl phenyl)substituted propanes or 2-methyl-1-nitrilo-or 2-methyl-1-hydroxylamino-3-(methoxyphenyl) propane, organoleptic uses thereof and processes for preparing same | INT FLAVORS & FRAGRANCES INC (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0531636-B1 | Process for preparing phenyl butyronitriles and perfumery use of 2,2-dimethyl-4-phenyl valeronitrile | INT FLAVORS & FRAGRANCES INC (US) | 1995-10-18 | — | — | EP | disclosed |
| EP-0347596-B1 | Bleaching composition | INT FLAVORS & FRAGRANCES INC (US) | 1995-07-12 | — | — | EP | disclosed |
| EP-0383446-B1 | 2,4,4-Trisubstituted tetrahydropyranyl esters and organoleptic uses thereof | INT FLAVORS & FRAGRANCES INC (US) | 1995-05-03 | — | — | EP | disclosed |
| US-5236897-A | Reacting isobutyronitrile with 2- or 4-vinyl pyridine; augments and enhances aromas | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1993-08-17 | — | — | US | disclosed |
| EP-0531636-A1 | Process for preparing phenyl butyronitriles and perfumery use of 2,2-dimethyl-4-phenyl valeronitrile | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| EP-0383446-A2 | 2,4,4-Trisubstituted tetrahydropyranyl esters and organoleptic uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1990-08-22 | — | — | EP | disclosed |
| EP-0347596-A2 | Bleaching composition | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1989-12-27 | — | — | EP | disclosed |
| US-4863631-A | Dimethyl substituted alkyl nitriles, perfume and bleach compositions containing same organoleptic uses thereof and process intermediates for producing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1989-09-05 | — | — | US | disclosed |
| US-4822515-A | Ethyl norbornyl alkyl ethers, organoleptic uses thereof and process for preparing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1989-04-18 | — | — | US | disclosed |
| US-4772411-A | ETHYL TRICYCLOHEPTYL ALKYL ETHERS, BLEACHES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0042734-B1 | OLEFIN DIMERS, DERIVATIVES THEREOF AND ORGANOLEPTIC USES THEREOF | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1985-03-20 | — | — | EP | disclosed |
| US-4390448-A | Perfumed stable aqueous hypochlorite bleach compositions containing 2-methyl-2-octanol and thickened variation thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1983-06-28 | — | — | US | disclosed |
| US-4342663-A | Use of mixture of aliphatic C10 branched olefins in augmenting or enhancing the aroma of articles subjected to action of aqueous hypochlorites | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 1982-08-03 | — | — | US | disclosed |
| US-4330425-A | Use of mixture of aliphatic C10 branched olefin epoxides in augmenting or enhancing the aroma of articles subjected to action of aqueous hypochlorites | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1982-05-18 | — | — | US | disclosed |
| EP-0042734-A2 | Olefin dimers, derivatives thereof and organoleptic uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-12-30 | — | — | EP | disclosed |