Known targets — ChEMBL curated mechanism
S1PR1S1PR2S1PR3S1PR4S1PR5rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.78 |
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | GLA | P06280 | 1/20 | 0.78 |
| ▸ | HPGD | P15428 | 1/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.78 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.78 |
| ▸ | BLM | P54132 | 1/20 | 0.78 |
| ▸ | CA1 | P00915 | 11/20 | 0.52 |
| ▸ | CA2 | P00918 | 11/20 | 0.52 |
| ▸ | CA9 | Q16790 | 9/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | CA3 | P07451 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL18315185 | 1.00 | RECQL (0.78) | RECQLTSHRGLAHPGDMAPK1 | |
| Octadecyl Sulfate SCHEMBL9771924 | 1.00 | RECQL (0.78) | RECQLTSHRGLAHPGDMAPK1 | |
| Octadecyl Sulfate SCHEMBL9771950 | 0.96 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL7537883 | 0.96 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL15283 | 0.96 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL23674209 | 0.96 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL7537830 | 0.96 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL7994677 | 0.96 | RECQL (0.78) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL21641350 | 0.96 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL11022896 | 0.96 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143335-B2 | Resin, filler, solvent and such as sodium lauryl sulfate foaming agent; free of cationic acrylamide copolymer; manufacturing wood based boards; low cost, durability; uniform, fast spreadability | MOMENTIVE SPECIALTY CHEMICALS INC. (US) | 2012-03-27 | — | — | US | claimed |
| EP-1471104-B1 | Adhesive composition | HEXION SPECIALTY CHEMICALS OY (FI) | 2008-10-08 | — | — | EP | claimed |
| US-20080242753-A1 | ADHESIVE COMPOSITION | JPMORGAN CHASE BANK, N.A. | 2008-10-02 | — | — | US | claimed |
| US-20060247345-A1 | Adhesive composition | WILMINGTON TRUST COMPANY, AS COLLATERAL AGENT | 2006-11-02 | — | — | US | claimed |
| EP-1471104-A1 | Adhesive composition | Bakelite Oy (FI) | 2004-10-27 | — | — | EP | claimed |
| WO-2004085521-A1 | ADHESIVE COMPOSITION | BAKELITE OY (FI) | 2004-10-07 | — | — | WO | claimed |
| EP-0272234-B2 | Apparatus for diverting electrostatic fields, for instance from television viewing screens | SCREEN GUARD PRODUKTION AB UB (SE) | 1995-06-21 | — | — | EP | claimed |
| EP-0231997-B1 | SHAMPOO | UNILEVER PLC (GB) | 1992-08-05 | — | — | EP | claimed |
| US-4856101-A | Apparatus for diverting electrostatic fields, for instance from television viewing screens | JONSON TEKNIK KB (SE) | 1989-08-08 | — | — | US | claimed |
| EP-0272234-A2 | Apparatus for diverting electrostatic fields, for instance from television viewing screens | SCREEN GUARD PRODUKTION AB Ub (SE) | 1988-06-22 | — | — | EP | claimed |
| EP-0231997-A2 | Shampoo | UNILEVER PLC (GB) | 1987-08-12 | — | — | EP | claimed |
| US-4657966-A | BIMODAL PARTICLE DISTRIBUTION; MICELLE FORMING SURFACTANT OR A UNIMODAL SEED LATEX | POLYSAR LIMITED (CA) | 1987-04-14 | — | — | US | claimed |
| US-4574141-A | Method for producing graft-copolymers of vinyl chloride and polyfluorine resin by copolymerization | FORMOSA PLASTICS CORPORATION (TW) | 1986-03-04 | — | — | US | claimed |
| CN-118139633-A | Probiotic composition for inhibiting fungal proliferation | 莱托生物股份有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-117835951-A | Soluble solid articles containing silicone | 宝洁公司 | 2024-04-05 | — | — | CN | disclosed |
| US-11826450-B2 | Cosmetic compositions | KAO CORPORATION S.A. (ES) | 2023-11-28 | — | — | US | disclosed |
| US-4321256-A | Shampoo containing a polyglycol-polyamine condensation resin and a phosphate ester | LEVER BROTHERS COMPANY (US) | 1982-03-23 | — | — | US | disclosed |
| US-4298494-A | CONTAINING CATIONIC DERIVATIVE OF A POLYGALACTOMANNAN AS A HAIR CONDITIONER | LEVER BROTHERS COMPANY (US) | 1981-11-03 | — | — | US | disclosed |
| EP-0024799-A1 | Conditioning shampoo, process for preparing it, dispenser containing it and a method of treating hair | UNILEVER PLC (GB) | 1981-03-11 | — | — | EP | disclosed |
| EP-0018717-A1 | Shampoo | UNILEVER PLC (GB) | 1980-11-12 | — | — | EP | disclosed |