Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 10/20 | 0.52 |
| ▸ | CA2 known ✓ | P00918 | 10/20 | 0.52 |
| ▸ | CA12 known ✓ | O43570 | 3/20 | 0.52 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.52 |
| ▸ | FGF1 known ✓ | P05230 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.85 |
| ▸ | TSHR | P16473 | 2/20 | 0.85 |
| ▸ | GLA | P06280 | 1/20 | 0.85 |
| ▸ | HPGD | P15428 | 1/20 | 0.85 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.85 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.85 |
| ▸ | BLM | P54132 | 1/20 | 0.85 |
| ▸ | CA9 | Q16790 | 8/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | CA3 | P07451 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL11756362 | 1.00 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL1978126 | 1.00 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL7537883 | 1.00 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL15283 | 1.00 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL355997 | 1.00 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL23674209 | 1.00 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Octadecyl Sulfate SCHEMBL9771950 | 1.00 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL11022896 | 1.00 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL21641350 | 1.00 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 | |
| Ether SCHEMBL324781 | 1.00 | RECQL (0.85) | RECQLTSHRGLAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020223168-A1 | COMPOSITIONS AND METHODS FOR REMOVING SEMI-PERMANENT HAIR DYES | L'OREAL (FR) | 2020-11-05 | — | — | WO | claimed |
| US-20200345606-A1 | COMPOSITIONS AND METHODS FOR REMOVING SEMI-PERMANENT HAIR DYES | L'OREAL (FR) | 2020-11-05 | — | — | US | claimed |
| US-20120189956-A1 | SOLVENT-FREE TONER PROCESSES | XEROX CORPORATION (US) | 2012-07-26 | — | — | US | claimed |
| WO-2023159563-A1 | COMPOSITION FOR SKIN CARE AND/OR CLEANSING | L'OREAL (FR) | 2023-08-31 | — | — | WO | disclosed |
| CN-110383171-B | Photosensitive resin composition for flexographic printing plate, flexographic printing original plate, flexographic printing plate, and copolymer | 旭化成株式会社 | 2023-07-28 | — | — | CN | disclosed |
| US-20210369582-A1 | METHODS AND COMPOSITIONS FOR REMOVING COLOR FROM COLOR-TREATED HAIR | L'OREAL (FR) | 2021-12-02 | — | — | US | disclosed |
| US-11173102-B1 | Methods and compositions for removing color from color-treated hair | L'OREAL (FR) | 2021-11-16 | — | — | US | disclosed |
| US-11154479-B1 | Methods of removing color from color-treated hair | L'OREAL (FR) | 2021-10-26 | — | — | US | disclosed |
| WO-2020223168-A1 | COMPOSITIONS AND METHODS FOR REMOVING SEMI-PERMANENT HAIR DYES | L'OREAL (FR) | 2020-11-05 | — | — | WO | disclosed |
| US-20200345606-A1 | COMPOSITIONS AND METHODS FOR REMOVING SEMI-PERMANENT HAIR DYES | L'OREAL (FR) | 2020-11-05 | — | — | US | disclosed |
| US-20120189956-A1 | SOLVENT-FREE TONER PROCESSES | XEROX CORPORATION (US) | 2012-07-26 | — | — | US | disclosed |
| US-4863631-A | Dimethyl substituted alkyl nitriles, perfume and bleach compositions containing same organoleptic uses thereof and process intermediates for producing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1989-09-05 | — | — | US | disclosed |
| US-4822515-A | Ethyl norbornyl alkyl ethers, organoleptic uses thereof and process for preparing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1989-04-18 | — | — | US | disclosed |
| US-4818523-A | LAURYL TRIMETHYL AMMONIUM CHLORIDE, ALKANOLS, CYCLIC OR LINEAR SILICONES; STABILITY | COLGATE-PALMOLIVE COMPANY (US) | 1989-04-04 | — | — | US | disclosed |
| US-4772411-A | ETHYL TRICYCLOHEPTYL ALKYL ETHERS, BLEACHES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0042734-B1 | OLEFIN DIMERS, DERIVATIVES THEREOF AND ORGANOLEPTIC USES THEREOF | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1985-03-20 | — | — | EP | disclosed |
| US-4390448-A | Perfumed stable aqueous hypochlorite bleach compositions containing 2-methyl-2-octanol and thickened variation thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1983-06-28 | — | — | US | disclosed |
| US-4342663-A | Use of mixture of aliphatic C10 branched olefins in augmenting or enhancing the aroma of articles subjected to action of aqueous hypochlorites | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 1982-08-03 | — | — | US | disclosed |
| US-4330425-A | Use of mixture of aliphatic C10 branched olefin epoxides in augmenting or enhancing the aroma of articles subjected to action of aqueous hypochlorites | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1982-05-18 | — | — | US | disclosed |
| EP-0042734-A2 | Olefin dimers, derivatives thereof and organoleptic uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200345606-A1 | COMPOSITIONS AND METHODS FOR REMOVING SEMI-PERMANENT HAIR DYES | CYCS, TYR, DNMT1 | CA1 876/4885CA2 716/4885CA12 128/4885 |
| US-11173102-B1 | Methods and compositions for removing color from color-treated hair | TYR, POLR1C, CYCS | CA1 821/4885CA2 202/4885CA12 70/4885 |
| US-11154479-B1 | Methods of removing color from color-treated hair | TYR, IK, HLA-C | CA1 811/4885CA2 181/4885CA12 78/4885 |
| US-20210369582-A1 | METHODS AND COMPOSITIONS FOR REMOVING COLOR FROM COLOR-TREATED HAIR | TYR, POLR1C, CYCS | CA1 821/4885CA2 202/4885CA12 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.