Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989163 | 0.88 | PTPN11 (0.48) | PPARALMNAMAPK1L3MBTL1CA1 | |
| SCHEMBL7995609 | 0.84 | S1PR1 (0.40) | PPARAS1PR1KDM4ESMN1; SMN2LSS | |
| SCHEMBL7994778 | 0.81 | SLC2A1 (0.41) | PPARAS1PR1KDM4ENPC1MAPT | |
| SCHEMBL7987543 | 0.80 | ABCB1 (0.44) | S1PR1KDM4EMAPTSMN1; SMN2S1PR3 | |
| SCHEMBL7994780 | 0.80 | MAOB (0.53) | S1PR1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7988818 | 0.78 | MAOB (0.48) | NPC1MAPTRAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL7991609 | 0.75 | MAOB (0.49) | NPC1RAB9ASMN1; SMN2L3MBTL1MAOA | |
| SCHEMBL7991453 | 0.73 | KDM4E (0.51) | KDM4EMAPTMAPK1MAOA | |
| SCHEMBL7989235 | 0.73 | ACHE (0.48) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7991147 | 0.70 | MAOB (0.47) | S1PR1KDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055117-A1 | NOVEL ISOQUINOLINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2001-08-02 | — | — | WO | disclosed |