Sugi Predict

Sugi Predict / Compounds / SCHEMBL7994816

SCHEMBL7994816

SCHEMBL7994816

CN(C(=O)Cl)C1CCOCC1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 2/20 0.42
▸ TSHR P16473 2/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ HSD11B1 P28845 1/20 0.36
▸ RAB9A P51151 5/20 0.36
▸ NPC1 O15118 4/20 0.36
▸ KMT2A Q03164 5/20 0.35
▸ MEN1 O00255 4/20 0.35
▸ PYGL P06737 1/20 0.35
▸ KDM4E B2RXH2 2/20 0.35
▸ CYP46A1 Q9Y6A2 1/20 0.33
▸ ABHD6 Q9BV23 2/20 0.31
▸ BCL2A1 Q16548 1/20 0.31
▸ HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8053344 0.84 — —
SCHEMBL9957386 0.81 — —
SCHEMBL9960095 0.80 PIK3CD (0.43) PIK3CDALDH1A1HSD11B1RAB9ANPC1
SCHEMBL11967749 0.80 PIK3CD (0.52) PIK3CDHSD11B1RAB9ANPC1KMT2A
SCHEMBL8054344 0.79 FAAH (0.45) TSHRALDH1A1RAB9ANPC1KMT2A
SCHEMBL19722917 0.78 PIK3CD (0.42) PIK3CDHSD11B1RAB9ANPC1KMT2A
SCHEMBL3958681 0.78 PIK3CD (0.42) PIK3CDHSD11B1RAB9ANPC1KMT2A
SCHEMBL227602 0.78 PIK3CD (0.42) PIK3CDALDH1A1HSD11B1RAB9ANPC1
SCHEMBL8977229 0.77 FAAH (0.48) TSHRALDH1A1RAB9ANPC1KMT2A
SCHEMBL427210 0.77 FAAH (0.48) TSHRALDH1A1RAB9ANPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250295683-A1 HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2025-09-25 — — US disclosed
EP-4527838-A1 HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2025-03-26 — — EP disclosed
WO-2023221797-A9 HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 四川科伦博泰生物医药股份有限公司 2025-02-13 — — WO disclosed
WO-2023221797-A1 HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 四川科伦博泰生物医药股份有限公司 2023-11-23 — — WO disclosed
EP-3638227-B1 SPIROCYCLIC INDOLINES AS IL-17 MODULATORS UCB Biopharma SRL (BE) 2022-08-10 — — EP disclosed
US-20220073485-A1 Functionalised Amine Derivatives as IL-17 Modulators UCB BIOPHARMA SRL (SOCIETE A RESPONSABILITE LIMITEE) (BE) 2022-03-10 — — US disclosed
CN-113260418-A Functionalized amine derivatives as IL-17 modulators UCB生物制药有限责任公司 2021-08-13 — — CN disclosed
US-11052076-B2 Spirocyclic indolines as IL-17 modulators UCB Biopharma SRL (BE) 2021-07-06 — — US disclosed
US-20200138797-A1 Spirocyclic Indolines as IL-17 Modulators UCB Biopharma SRL (BE) 2020-05-07 — — US disclosed
EP-3638227-A1 SPIROCYCLIC INDOLINES AS IL-17 MODULATORS UCB Biopharma SRL (BE) 2020-04-22 — — EP disclosed
US-20170217910-A1 INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES LEO LABORATORIES LIMITED (IE) 2017-08-03 — — US disclosed
US-9708286-B2 Ingenol-3-acylates III and ingenol-3-carbamates LEO LABORATORIES LIMITED (IE) 2017-07-18 — — US disclosed
US-20150291551-A1 INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES LEO LABORATORIES LIMITED (IE) 2015-10-15 — — US disclosed
US-9102687-B2 Ingenol-3-acylates III and ingenol-3-carbamates LEO LABORATORIES LIMITED (IE) 2015-08-11 — — US disclosed
US-20140303150-A1 INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES LEO LABORATORIES LIMITED (IE) 2014-10-09 — — US disclosed
EP-2655323-A1 INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES LEO LABORATORIES LIMITED (IE) 2013-10-30 — — EP disclosed
WO-2012083953-A1 INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES LEO PHARMA A/S (DK) 2012-06-28 — — WO disclosed
US-6277790-B1 APPLYING PLANTS, SEEDS, SOILS OR ENVIRONMENT BASF AKTIENGESELLSCHAFT (DE) 2001-08-21 — — US disclosed
EP-1003741-A1 SUBSTITUTED HERBICIDE TETRAZOLINONECARBOXYLIC ACID AMIDES BASF AKTIENGESELLSCHAFT (DE) 2000-05-31 — — EP disclosed
WO-1999007702-A1 SUBSTITUTED HERBICIDE TETRAZOLINONECARBOXYLIC ACID AMIDES BASF AKTIENGESELLSCHAFT (DE) 1999-02-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220073485-A1 Functionalised Amine Derivatives as IL-17 Modulators IL17A, IL15, IL2 PIK3CD 3567/4885TSHR 1151/4885ALDH1A1 437/4885
US-11052076-B2 Spirocyclic indolines as IL-17 modulators IL17A, IL2, IL18 PIK3CD 2222/4885TSHR 1408/4885ALDH1A1 939/4885
US-20200138797-A1 Spirocyclic Indolines as IL-17 Modulators IL17A, IL2, IL18 PIK3CD 2222/4885TSHR 1408/4885ALDH1A1 939/4885
US-20170217910-A1 INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES RXRB, RXRA, RXRG PIK3CD 2102/4885TSHR 647/4885ALDH1A1 2810/4885
US-20250295683-A1 HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF CYP4F11, CYP51A1, CYP4A11 PIK3CD 2307/4885TSHR 3326/4885ALDH1A1 729/4885
US-20150291551-A1 INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES RXRB, RXRA, RXRG PIK3CD 2102/4885TSHR 647/4885ALDH1A1 2810/4885
US-20140303150-A1 INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES RXRB, RXRA, RXRG PIK3CD 2102/4885TSHR 647/4885ALDH1A1 2810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.