SCHEMBL427210

SCHEMBL427210

CN(C(=O)Cl)C1CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.48
PHGDH O43175 1/20 0.48
MGLL Q99685 1/20 0.48
TSHR P16473 2/20 0.47
HPGD P15428 1/20 0.47
ALDH1A1 P00352 3/20 0.47
ATM Q13315 1/20 0.44
ADH1C P00326 1/20 0.43
ADH1A P07327 1/20 0.43
NPC1 O15118 4/20 0.41
POLB P06746 4/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
NPSR1 Q6W5P4 1/20 0.41
RAB9A P51151 4/20 0.40
NPBWR1 P48145 1/20 0.40
ABCC1 P33527 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8977229 1.00 FAAH (0.48) FAAHPHGDHMGLLTSHRHPGD
SCHEMBL7105501 0.98 FAAH (0.47) FAAHPHGDHMGLLTSHRHPGD
SCHEMBL8054344 0.98 FAAH (0.45) FAAHPHGDHMGLLTSHRHPGD
SCHEMBL9957386 0.95
SCHEMBL8053344 0.87
SCHEMBL27862797 0.82 FAAH (0.45) FAAHPHGDHMGLLTSHRHPGD
SCHEMBL8977352 0.80 ALDH1A1 (0.35) FAAHPHGDHMGLLTSHRHPGD
SCHEMBL17704770 0.80 FAAH (0.52) FAAHPHGDHMGLLTSHRHPGD
SCHEMBL7994505 0.79 TSHR (0.38) TSHRHPGDALDH1A1
SCHEMBL16424652 0.79 EPHX1 (0.41) TSHRALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747247-A1 NOVEL FATTY ACID AMIDE HYDROLASE MODULATORS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF Apogee Pharmaceuticals, Inc. (CA) 2026-05-27 EP disclosed
US-12410137-B2 Fatty acid amide hydrolase modulators, compositions comprising the same and uses thereof APOGEE PHARMACEUTICALS, INC. (CA) 2025-09-09 US disclosed
US-20250129027-A1 FATTY ACID AMIDE HYDROLASE MODULATORS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF APOGEE PHARMACEUTICALS, INC. (CA) 2025-04-24 US disclosed
WO-2025015420-A1 NOVEL FATTY ACID AMIDE HYDROLASE MODULATORS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF APOGEE PHARMACEUTICALS, INC. (CA) 2025-01-23 WO disclosed
US-11078163-B2 Processes for the synthesis of substituted urea compounds Bial-Portela & Cª, S.A. (PT) 2021-08-03 US disclosed
CN-105934431-B Process for preparing substituted urea compounds 比亚尔-珀特拉和CA股份公司 2020-11-17 CN disclosed
US-20200140391-A1 Processes for the Synthesis of Substituted Urea Compounds BIAL-PORTELA & CA, S.A. (PT) 2020-05-07 US disclosed
US-10583140-B2 Ingenol analogs, pharmaceutical compositions and methods of use thereof GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2020-03-10 US disclosed
EP-3097082-B1 PROCESSES FOR THE SYNTHESIS OF SUBSTITUTED UREA COMPOUNDS BIAL PORTELA & CA SA (PT) 2019-10-02 EP disclosed
US-20190030029-A1 INGENOL ANALOGS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2019-01-31 US disclosed
US-5403816-A Picolinic acid derivative and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1995-04-04 US disclosed
EP-0567133-A1 Picolinic acid derivative and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1993-10-27 EP disclosed
US-4973588-A IMPROVED BRAIN FUNCTION AT REDUCED OXYGEN LEVELS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-11-27 US disclosed
US-4067726-A 3-Ureido phenylacetamide herbicides BAYER AKTIENGESELLSCHAFT (DT) 1978-01-10 US disclosed
US-4053298-A HERBICIDAL COMPOSITIONS CONTAINING 1-THIADIAZOLYL-6-CARBAMOYLOXYTETRAHYDROPYRIMIDINONES AND METHODS THEREFOR VELSICOL CHEMICAL CORPORATION (US) 1977-10-11 US disclosed
US-4023957-A Herbicidal 1-thiadiazolyl-5-carbamoyloxyimidazolidinones VELSICOL CHEMICAL CORPORATION (US) 1977-05-17 US disclosed
US-3989710-A POSTEMERGENCE HERBICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-11-02 US disclosed
US-3978107-A NOVEL CYCLOHEXYL CARBAMATES AND HERBICIDAL AND ACARICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DT) 1976-08-31 US disclosed
US-3951976-A 1-Thiadiazoly-6-carbamoyloxytetrahydropyrimidinones VELSICOL CHEMICAL CORPORATION (US) 1976-04-20 US disclosed
US-3937824-A COMPOSITIONS AND METHODS OF KILLING INSECTS AND ACARIDS USING ALKOXYIMINO CARBAMOYLOXY PHOSPHORUS COMPOUNDS VELSICOL CHEMICAL CORPORATION (US) 1976-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200140391-A1 Processes for the Synthesis of Substituted Urea Compounds GRHPR, REN, ODC1 FAAH 3163/4885PHGDH 1126/4885MGLL 3511/4885
US-20250129027-A1 FATTY ACID AMIDE HYDROLASE MODULATORS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF FAAH, FAAH2, MGLL FAAH 1/4885PHGDH 181/4885MGLL 3/4885
US-12410137-B2 Fatty acid amide hydrolase modulators, compositions comprising the same and uses thereof FAAH, FAAH2, MGLL FAAH 1/4885PHGDH 181/4885MGLL 3/4885
US-20190030029-A1 INGENOL ANALOGS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF ERG28, PTH1R, CCR5 FAAH 3126/4885PHGDH 2157/4885MGLL 309/4885
US-10583140-B2 Ingenol analogs, pharmaceutical compositions and methods of use thereof ERG28, PTH1R, CCR5 FAAH 3126/4885PHGDH 2157/4885MGLL 309/4885
US-11078163-B2 Processes for the synthesis of substituted urea compounds GRHPR, REN, ODC1 FAAH 3163/4885PHGDH 1126/4885MGLL 3511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.